Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mafenide
Drug ID BADD_D01337
Description Mafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns.
Indications and Usage Indicated for use as an adjunctive topical antimicrobial agent to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds.[label]
Marketing Status approved; vet_approved
ATC Code D06BA03
DrugBank ID DB06795
KEGG ID D02351
MeSH ID D008272
PubChem ID 3998
TTD Drug ID D0K1QD
NDC Product Code Not Available
UNII 58447S8P4L
Synonyms Mafenide | Maphenid | Mafenide Acetate | Sulfamylon | Marfanil | Napaltan | 4-Homosulfanilamide | 4 Homosulfanilamide | Sulfabenzamine | Bensulfamide | Mafylon
Chemical Information
Molecular Formula C7H10N2O2S
CAS Registry Number 138-39-6
SMILES C1=CC(=CC=C1CN)S(=O)(=O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acidosis14.01.03.002--
Blister12.01.06.002; 23.03.01.001---
Burning sensation08.01.09.029; 17.02.06.001---
Dermatitis23.03.04.002---
Dermatitis bullous23.03.01.002--
Diarrhoea07.02.01.001--
Disseminated intravascular coagulation01.01.02.002; 24.01.01.010--
Eosinophilia01.02.04.001--
Erythema23.03.06.001---
Face oedema08.01.07.003; 10.01.05.002; 23.04.01.004--
Glucose-6-phosphate dehydrogenase deficiency01.06.05.001; 03.08.03.001; 14.14.03.001---
Haemoglobin13.01.05.018---
Haemolytic anaemia01.06.03.002---
Hyperventilation19.01.02.004; 22.02.01.006---
Metabolic acidosis14.01.01.003---
Pain08.01.08.004--
Pancytopenia01.03.03.003---
PCO213.02.01.017---
Pruritus23.03.12.001--
Rash23.03.13.001---
Swelling08.01.03.015---
Tachypnoea22.02.01.014---
Urticaria10.01.06.001; 23.04.02.001--
Skin maceration23.03.03.016---
Haemorrhage24.07.01.002---
Porphyrin metabolism disorder03.08.01.006; 09.01.10.004; 14.14.01.006---
Skin abrasion12.01.06.010; 23.03.11.018---
Bone marrow failure01.03.03.005--
Accidental exposure to product12.09.01.001---
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ADReCS-Target
Drug Name ADR Term Target
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