Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lisuride
Drug ID BADD_D01301
Description An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists).
Indications and Usage For the management of Parkinson's Disease
Marketing Status approved; investigational
ATC Code G02CB02; N02CA07
DrugBank ID DB00589
KEGG ID D08132
MeSH ID D008090
PubChem ID 28864
TTD Drug ID D0X7KB
NDC Product Code Not Available
UNII E0QN3D755O
Synonyms Lisuride | Lysurid | Methylergol Carbamide | Carbamide, Methylergol | Arolac | Cuvalit | Dopergine | Dopergin | Revanil | Lisuride, (8alpha)-(+-)-Isomer | Lysenyl | Lisuride Maleate | Maleate, Lisuride | Lysuride Hydrogen Maleate | Hydrogen Maleate, Lysuride | Lisuride Maleate (1:1) | Lisuride Maleate, (8beta)-Isomer | Lisuride Mesylate | Mesylate, Lisuride | Lisuride Phosphate (1:1) | Lisuride Hydrochloride | Hydrochloride, Lisuride
Chemical Information
Molecular Formula C20H26N4O
CAS Registry Number 18016-80-3
SMILES CCN(CC)C(=O)NC1CN(C2CC3=CNC4=CC=CC(=C34)C2=C1)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001---
Aggression19.05.01.001---
Anxiety19.06.02.002--
Asthenia08.01.01.001---
Binge eating19.09.01.001---
Blood pressure increased13.14.03.005---
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Cough22.02.03.001--
Dehydration14.05.05.001--
Dementia17.03.01.001; 19.20.02.001---
Disorientation17.02.05.015; 19.13.01.002---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Dyspnoea02.11.05.003; 22.02.01.004--
Erythromelalgia23.06.05.002; 24.03.01.001---
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014---
Gastrointestinal disorder07.11.01.001---
Hallucination19.10.04.003--
Headache17.14.01.001--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hyperprolactinaemia05.03.01.002---
Immune system disorder10.02.01.001---
Infection11.01.08.002---
Insomnia17.15.03.002; 19.02.01.002--
Libido increased19.08.03.002; 21.03.02.007--
Myoclonus17.02.05.008---
Nervous system disorder17.02.10.001---
Nightmare19.02.03.003---
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