| Pharmaceutical Information |
| Drug Name |
Lindane |
| Drug ID |
BADD_D01294 |
| Description |
An organochlorine insecticide that has been used as a pediculicide and a scabicide. Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment. In Canada, Lindane is not recommmended as a first-line therapy due to reports of resistance, neurotoxicity, and bone marrow suppression, but has been approved by the FDA as a second-line therapy for topical treatment of pediculosis capitis (head lice), pediculosis pubis (pubic lice), or scabies in patients greater than two years of age who cannot tolerate or have failed first-line treatment. Lindane is still allowed for pharmaceutical use until 2015. |
| Indications and Usage |
For the treatment of patients infested with Sarcoptes scabiei or pediculosis capitis who have either failed to respond to adequate doses, or are intolerant of other approved therapies. |
| Marketing Status |
approved; withdrawn |
| ATC Code |
P03AB02 |
| DrugBank ID |
DB00431
|
| KEGG ID |
D00360
|
| MeSH ID |
D001556
|
| PubChem ID |
727
|
| TTD Drug ID |
D0Q5IN
|
| NDC Product Code |
Not Available |
| UNII |
59NEE7PCAB
|
| Synonyms |
Hexachlorocyclohexane | Hexachlorane | Benzene Hexachloride | Hexachloride, Benzene | Epsilon-hexachlorocyclohexane | Epsilon hexachlorocyclohexane | Zeta-hexachlorocyclohexane | Zeta hexachlorocyclohexane | Lindane | gamma-Benzene Hexachloride | Hexachloride, gamma-Benzene | gamma Benzene Hexachloride | Gamma-666 | Gamma 666 | Gammexane | gamma-HCH | gamma HCH | gamma-Hexachlorocyclohexane | gamma Hexachlorocyclohexane | BHC Insecticide | Insecticide, BHC | PMS-Lindane | PMS Lindane | Kwell | Scabecid | Jacutin | Scabene | Tetocid | Scabisan | Eta-hexachlorocyclohexane | Eta hexachlorocyclohexane | Delitex |
|
| Chemical Information |
| Molecular Formula |
C6H6Cl6 |
| CAS Registry Number |
319-84-6 |
| SMILES |
C1(C(C(C(C(C1Cl)Cl)Cl)Cl)Cl)Cl |
| Chemical Structure |
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| ADRs Induced by Drug |
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