Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Levobunolol hydrochloride
Drug ID BADD_D01268
Description A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
Indications and Usage For lowering intraocular pressure (IOP) and may be used in patients with chronic open-angle glaucoma or ocular hypertension.
Marketing Status approved
ATC Code S01ED03
DrugBank ID DB01210
KEGG ID D01025
MeSH ID D002040
PubChem ID 5284409
TTD Drug ID D00IUG
NDC Product Code 65085-0029; 24208-505; 17337-0525
UNII O90S49LDHH
Synonyms Levobunolol | Apo-Levobunolol | Apo Levobunolol | ApoLevobunolol | Betagan | Levobunolol Hydrochloride | Novo-Levobunolol | Novo Levobunolol | NovoLevobunolol | W-7000A | W 7000A | W7000A | ratio-Levobunolol | ratio Levobunolol | Ultracortenol | Vistagan | AKBeta | PMS-Levobunolol | PMS Levobunolol | PMSLevobunolol
Chemical Information
Molecular Formula C17H26ClNO3
CAS Registry Number 27912-14-7
SMILES CC(C)(C)NCC(COC1=CC=CC2=C1CCCC2=O)O.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Alopecia23.02.02.001--
Arrhythmia02.03.02.001---
Asthenia08.01.01.001---
Ataxia08.01.02.004; 17.02.02.001--
Atrioventricular block02.03.01.002---
Blood pressure decreased13.14.03.002---
Bradycardia02.03.02.002---
Bronchospasm10.01.03.012; 22.03.01.004--
Cardiac arrest02.03.04.001--
Cardiac failure congestive02.05.01.002---
Cerebral ischaemia17.08.01.005; 24.04.06.003--
Cerebrovascular disorder17.08.02.002; 24.03.05.002---
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Confusional state17.02.03.005; 19.13.01.001--
Conjunctivitis06.04.01.002; 11.01.06.012--
Depression19.15.01.001--
Diarrhoea07.02.01.001--
Diplopia06.02.06.002; 17.17.01.005---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dyspnoea02.11.05.003; 22.02.01.004--
Eyelid ptosis06.05.01.002; 17.17.02.004---
Headache17.14.01.001--
Heart rate decreased13.14.04.001---
Hypersensitivity10.01.03.003--
Hypoaesthesia eye06.01.01.007; 17.02.06.019---
Hypoglycaemia05.06.03.001; 14.06.03.001--
Hypotension24.06.03.002--
Iridocyclitis06.04.03.001---
Keratitis06.04.02.002--
Lethargy08.01.01.008; 17.02.04.003; 19.04.04.004--
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