Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Lercanidipine
Drug ID BADD_D01255
Description Lercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
Indications and Usage For the treatment of Hypertension, management of angina pectoris and Raynaud's syndrome
Marketing Status approved; investigational
ATC Code C08CA13
DrugBank ID DB00528
KEGG ID D08111
MeSH ID C060343
PubChem ID 65866
TTD Drug ID D0P6ZH
NDC Product Code Not Available
UNII V7XTJ4R0BH
Synonyms lercanidipine | methyl-1,1-dimethyl-2-(N-(3,3-diphenylpropyl)-N-methylamino)ethyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | lercanidipine hydrochloride | Zanidip | Lerdip | Lercadip | REC 15-2375 | REC-15-2375
Chemical Information
Molecular Formula C36H41N3O6
CAS Registry Number 100427-26-7
SMILES CC1=C(C(C(=C(N1)C)C(=O)OC(C)(C)CN(C)CCC(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC(=CC=C4)[N+ ](=O)[O-])C(=O)OC
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Agranulocytosis01.02.03.001---
Alanine aminotransferase increased13.03.04.005--
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Angina pectoris02.02.02.002; 24.04.04.002--
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Anxiety19.06.02.002--
Aphthous ulcer07.05.06.002---
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Aspartate aminotransferase increased13.03.04.011--
Asthenia08.01.01.001---
Asthma10.01.03.010; 22.03.01.002---
Blood creatinine increased13.13.01.004--
Blood triglycerides increased13.12.03.001---
Blood urea increased13.13.01.006---
Body temperature increased13.15.01.001---
Bronchospasm10.01.03.012; 22.03.01.004--
Cardiac failure02.05.01.001--
Cardiovascular disorder02.11.01.010; 24.03.02.009---
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Cholestasis09.01.01.001---
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Cough22.02.03.001--
Dermatitis23.03.04.002---
Dermatitis atopic10.01.04.004; 23.03.04.016---
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