Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Kanamycin sulfate
Drug ID BADD_D01227
Description Kanamycin (also known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections. Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is kanamycin sulfate.
Indications and Usage For treatment of infections where one or more of the following are the known or suspected pathogens: E. coli, Proteus species (both indole-positive and indole-negative), E. aerogenes, K. pneumoniae, S. marcescens, and Acinetobacter species.
Marketing Status approved; investigational; vet_approved
ATC Code S01AA24; A07AA08; J01GB04
DrugBank ID DB01172
KEGG ID D00866; D03262
MeSH ID D007612
PubChem ID 441374
TTD Drug ID D0YV1Q
NDC Product Code 42513-0002
UNII J80EX28SMQ
Synonyms Kanamycin | Kantrex | Kanamycin A | Kanamycin Sulfate
Chemical Information
Molecular Formula C18H38N4O15S
CAS Registry Number 3847-27-6
SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N.OS(=O)(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Apnoea22.02.01.001--
Azotaemia20.01.01.001---
Carotene decreased13.02.05.005---
Deafness04.02.01.001---
Diarrhoea07.02.01.001--
Faecal fat increased13.05.02.002---
Headache17.14.01.001--
Malabsorption07.17.01.001; 14.02.01.004--
Meniere's disease04.04.02.003; 07.01.07.007; 17.02.12.003---
Nausea07.01.07.001--
Neurotoxicity12.03.01.011; 17.02.10.002---
Nystagmus06.05.02.006; 17.02.02.006--
Oliguria20.01.03.004---
Paraesthesia17.02.06.005; 23.03.03.094--
Paralysis17.01.04.004---
Pyrexia08.05.02.003--
Rash23.03.13.001---
Tinnitus04.04.01.002; 17.04.07.004--
Vertigo04.04.01.003; 17.02.12.002--
Vestibular disorder04.04.02.001; 17.02.02.008--
Vomiting07.01.07.003--
Balance disorder08.01.03.081; 17.02.02.007---
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