Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Kanamycin
Drug ID BADD_D01226
Description Kanamycin (also known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections. Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is kanamycin sulfate.
Indications and Usage For treatment of infections where one or more of the following are the known or suspected pathogens: E. coli, Proteus species (both indole-positive and indole-negative), E. aerogenes, K. pneumoniae, S. marcescens, and Acinetobacter species.
Marketing Status approved; investigational; vet_approved
ATC Code A07AA08; J01GB04; S01AA24
DrugBank ID DB01172
KEGG ID D03262; D00866
MeSH ID D007612
PubChem ID 6032
TTD Drug ID D0YV1Q
NDC Product Code Not Available
UNII RUC37XUP2P
Synonyms Kanamycin | Kantrex | Kanamycin A | Kanamycin Sulfate
Chemical Information
Molecular Formula C18H36N4O11
CAS Registry Number 59-01-8
SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Albuminuria20.02.01.001---
Apnoea22.02.01.001--
Application site irritation08.02.01.003; 12.07.01.003---
Application site pain08.02.01.004; 12.07.01.004---
Azotaemia20.01.01.001---
Body temperature increased13.15.01.001---
Deafness04.02.01.001---
Deafness neurosensory04.02.01.002; 17.04.07.001---
Dermatitis23.03.04.002---
Diarrhoea07.02.01.001--
Headache17.14.01.001--
Malabsorption07.17.01.001; 14.02.01.004--
Meniere's disease04.04.02.003; 07.01.07.007; 17.02.12.003---
Nausea07.01.07.001--
Nephropathy toxic12.03.01.010; 20.05.03.002---
Neurotoxicity12.03.01.011; 17.02.10.002---
Nystagmus06.05.02.006; 17.02.02.006--
Oliguria20.01.03.004---
Ototoxicity04.03.01.004; 12.03.01.012---
Pain08.01.08.004--
Paraesthesia17.02.06.005; 23.03.03.094--
Paralysis17.01.04.004---
Pyrexia08.05.02.003--
Rash23.03.13.001---
Red blood cells urine positive13.13.02.003---
Tinnitus04.04.01.002; 17.04.07.004--
Urinary casts13.13.02.014---
Vertigo04.04.01.003; 17.02.12.002--
Vestibular disorder04.04.02.001; 17.02.02.008--
Vomiting07.01.07.003--
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