Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Iloprost
Drug ID BADD_D01135
Description Iloprost is a synthetic analogue of prostacyclin PGI2 that dilates systemic and pulmonary arterial vascular beds. It is used to treat pulmonary arterial hypertension (PAH).
Indications and Usage Used for the treatment of pulmonary arterial hypertension.
Marketing Status Prescription; Discontinued
ATC Code B01AC11
DrugBank ID DB01088
KEGG ID D02721
MeSH ID D016285
PubChem ID 5311181
TTD Drug ID D05ZTH
NDC Product Code 54893-0017; 66215-302; 82231-109; 66215-303; 40016-013
Synonyms Iloprost | Ciloprost | ZK-36374 | ZK 36374 | ZK36374 | Ventavis
Chemical Information
Molecular Formula C22H32O4
CAS Registry Number 78919-13-8
SMILES CC#CCC(C)C(C=CC1C(CC2C1CC(=CCCCC(=O)O)C2)O)O
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.0010.002040%
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Acute respiratory failure14.01.04.004; 22.02.06.0010.000194%Not Available
Altered state of consciousness17.02.04.001; 19.07.01.0030.000556%Not Available
Ammonia increased13.03.01.0230.000371%Not Available
Amnesia17.03.02.001; 19.20.01.001--
Anaemia01.03.02.001--
Angina pectoris02.02.02.002; 24.04.04.0020.000556%
Angina unstable02.02.02.004; 24.04.04.0040.000371%Not Available
Ankle fracture12.04.01.005; 15.08.03.0050.000371%
Anxiety19.06.02.002--
Arrhythmia02.03.02.0010.001855%Not Available
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Ascites02.05.04.002; 07.07.01.001; 09.01.05.0030.001855%
Asphyxia12.01.08.011; 22.02.02.0010.001484%Not Available
Asthenia08.01.01.0010.005936%Not Available
Asthma10.01.03.010; 22.03.01.002--Not Available
Atrial fibrillation02.03.03.002--
Atrial flutter02.03.03.0030.000371%
Atrial septal defect02.04.02.009; 03.07.02.0020.000097%Not Available
Back pain15.03.04.0050.002597%
Bacteraemia11.01.11.0010.000371%
Blindness unilateral06.02.02.009; 17.17.01.0160.000371%Not Available
Blister12.01.06.002; 23.03.01.001--Not Available
Blood glucose abnormal13.02.02.0080.000556%Not Available
Blood glucose decreased13.02.02.0010.000371%Not Available
Blood potassium decreased13.11.01.0100.000371%Not Available
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