Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Idoxuridine
Drug ID BADD_D01131
Description An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
Indications and Usage For use in keratoconjunctivitis and keratitis caused by herpes simplex virus.
Marketing Status approved; investigational
ATC Code D06BB01; J05AB02; S01AD01
DrugBank ID DB00249
KEGG ID D00342
MeSH ID D007065
PubChem ID 5905
TTD Drug ID D09PZO
NDC Product Code Not Available
UNII LGP81V5245
Synonyms Idoxuridine | 5-Iodo-2'-deoxyuridine | 5 Iodo 2' deoxyuridine | IUdR | 5-Iododeoxyuridine | 5 Iododeoxyuridine | Iododeoxyuridine | Herplex Liquifilm | Liquifilm, Herplex | Idoxuridine, 123I-Labeled | 123I-Labeled Idoxuridine | Idoxuridine, 123I Labeled | Idoxuridine, 125I-Labeled | 125I-Labeled Idoxuridine | Idoxuridine, 125I Labeled | Idoxuridine, 131I-Labeled | 131I-Labeled Idoxuridine | Idoxuridine, 131I Labeled | Idoxuridine, 3H-Labeled | 3H-Labeled Idoxuridine | Idoxuridine, 3H Labeled | Stoxil | Idoxuridine, Radical Ion (1-) | Kerecide | NSC-39661 | NSC 39661 | NSC39661 | Oftan-IDU | Oftan IDU | OftanIDU | SK&F-14287 | Allergan 211 | Idoxuridine, Radical Ion (+1)
Chemical Information
Molecular Formula C9H11IN2O5
CAS Registry Number 54-42-2
SMILES C1C(C(OC1N2C=C(C(=O)NC2=O)I)CO)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blepharitis06.04.04.001; 23.03.04.012---
Burning sensation08.01.09.029; 17.02.06.001---
Conjunctivitis06.04.01.002; 11.01.06.012--
Eye irritation06.04.05.003---
Swelling08.01.03.015---
Vision blurred06.02.06.007; 17.17.01.010--
Vital dye staining cornea present13.07.04.010---
Conjunctival hyperaemia06.04.01.004---
Peripheral revascularisation25.03.01.002---
Corneal disorder06.08.01.004---
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