Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Framycetin
Drug ID BADD_D00975
Description A component of neomycin that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed)
Indications and Usage For the treatment of bacterial blepharitis, bacterial bonjunctivitis, corneal injuries, corneal ulcers and meibomianitis. For the prophylaxis of ocular infections following foreign body removal
Marketing Status approved
ATC Code D09AA01; R01AX08; S01AA07
DrugBank ID DB00452
KEGG ID D05140
MeSH ID D005601
PubChem ID 8378
TTD Drug ID D05JNI
NDC Product Code Not Available
UNII 4BOC774388
Synonyms Framycetin | Neomycin B | Antibiotic 10676 | Neomycin B Sulfate | Sulfate, Neomycin B | Framycetin Sulfate | Sulfate, Framycetin | Soframycin
Chemical Information
Molecular Formula C23H46N6O13
CAS Registry Number 119-04-0
SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Diarrhoea07.02.01.001--
Malabsorption07.17.01.001; 14.02.01.004--
Nausea07.01.07.001--
Nephropathy toxic12.03.01.010; 20.05.03.002---
Ototoxicity04.03.01.004; 12.03.01.012---
Steatorrhoea07.17.01.002---
Vomiting07.01.07.003--
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