| Pharmaceutical Information |
| Drug Name |
Ferric pyrophosphate |
| Drug ID |
BADD_D00884 |
| Description |
Ferric pyrophosphate is an iron replacement product. Free iron presents several side effects as it can catalyze free radical formation and lipid peroxidation as well as the presence of interactions of iron in plasma. The ferric ion is strongly complexed by pyrophosphate.[A31979] It presents an increasing interest as this insoluble form can be milder in the gastrointestinal tract and present higher bioavailability.[L1433] |
| Indications and Usage |
Ferric pyrophosphate is intended to be indicated for the treatment of iron loss or iron deficiency as a formulation with a milder gastrointestinal effect.[L1423, L1433]
Iron deficiency appears when the dietary intake does not meet the body's requirement or when there is chronic external blood loss. During acute blood loss, body iron stores are sufficient for accelerated erythropoiesis and restoration of iron homeostasis. But when the altered homeostasis remains for weeks to months then some supplement is needed. Some causes of iron deficiency include ectoparasitism, endoparasitism, hematuria, epistaxis, hemorrhagic skin, coagulopathy, thrombocytopenia, thrombocytopathia and gastrointestinal hemorrhage.[A31984] |
| Marketing Status |
experimental |
| ATC Code |
Not Available |
| DrugBank ID |
DB09147
|
| KEGG ID |
Not Available
|
| MeSH ID |
C049051
|
| PubChem ID |
24877
|
| TTD Drug ID |
D0Y2JM
|
| NDC Product Code |
Not Available |
| UNII |
QK8899250F
|
| Synonyms |
ferric pyrophosphate | Sunactive Fe | ferric pyrophosphate nonahydrate | JM-3100 | Actiferol Fe |
|
| Chemical Information |
| Molecular Formula |
Fe4(P2O7)3 |
| CAS Registry Number |
10058-44-3 |
| SMILES |
[O-]P(=O)([O-])OP(=O)([O-])[O-].[O-]P(=O)([O-])OP(=O)([O-])[O-].[O-]P(=O)([O-])O
P(=O)([O-])[O-].[Fe+3].[Fe+3].[Fe+3].[Fe+3] |
| Chemical Structure |
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| ADRs Induced by Drug |
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