| Drug Name |
Fenofibric acid |
| Drug ID |
BADD_D00874 |
| Description |
Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile,[A32038] prodrug ,[fenofibrate], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed for improved solubility, gastrointestinal absorption, and bioavailability, and more convenient administration.[A32038,A193362] |
| Indications and Usage |
For use as an adjunctive therapy to diet to: (a) reduce triglyceride levels in adult patients with severe hypertriglyceridemia, and (b) reduce elevated total cholesterol, low-density-lipoprotein (LDL-C), triglycerides, and apolipoprotein B, and to increase high-density-lipoprotein (HDL-C) in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). [FDA Label] |
| Marketing Status |
approved |
| ATC Code |
Not Available |
| DrugBank ID |
DB13873
|
| KEGG ID |
D11579
|
| MeSH ID |
C006012
|
| PubChem ID |
64929
|
| TTD Drug ID |
D0NF1U
|
| NDC Product Code |
68543-3161; 70436-169; 24979-109; 42571-348; 66064-1003; 0115-1555; 69315-282; 69844-022; 42385-944; 0074-3161; 24979-112; 42385-945; 46708-244; 59651-216; 62332-244; 17337-0411; 0074-3162; 69315-281; 42571-347; 46708-245; 59651-217; 70436-168; 0115-1554; 62332-245; 69844-023; 68543-3162 |
| UNII |
BGF9MN2HU1
|
| Synonyms |
fenofibric acid | 2-(4-(4'-chlorophenoxy)phenoxy)propionic acid | fenofibric acid sodium salt | fenofibric acid potassium salt | fenofibric acid, (R)-isomer | HCG 004 |
