Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Etomidate
Drug ID BADD_D00851
Description Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.
Indications and Usage Used in the induction of general anesthesia.
Marketing Status approved
ATC Code N01AX07
DrugBank ID DB00292
KEGG ID D00548
MeSH ID D005045
PubChem ID 667484
TTD Drug ID D02YPG
NDC Product Code 65145-127; 72572-160; 63804-2400; 25021-674; 0143-9507; 68382-545; 0409-6695; 51504-0012; 55150-221; 55150-222; 65219-445; 67457-902; 23155-160; 51662-1485; 65145-128; 51662-1542; 65841-818; 0404-9811; 0143-9506; 65219-447; 67457-903; 63660-0005; 0143-9310; 0143-9311; 72572-161
UNII Z22628B598
Synonyms Etomidate | Ethomidate | Radenarkon | Hypnomidate | R-26490 | R 26490 | R26490
Chemical Information
Molecular Formula C14H16N2O2
CAS Registry Number 33125-97-2
SMILES CCOC(=O)C1=CN=CN1C(C)C2=CC=CC=C2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Adrenal insufficiency05.01.02.001; 14.11.01.0040.000268%
Agitation17.02.05.012; 19.06.02.0010.000179%
Amnesia17.03.02.001; 19.20.01.0010.000179%
Apnoea22.02.01.001--
Arrhythmia02.03.02.001---
Bradycardia02.03.02.002---
Cardiac arrest02.03.04.0010.000179%
Disinhibition19.05.01.002---
Drug ineffective08.06.01.0060.005823%-
Dyskinesia17.01.02.006--
Epilepsy17.12.03.0020.000357%-
Hiccups07.01.06.009; 22.12.01.001--
Hypertension24.08.02.0010.000179%
Hypertonia15.05.04.007; 17.05.02.0010.001697%-
Hyperventilation19.01.02.004; 22.02.01.006---
Hypotension24.06.03.002--
Hypoventilation22.02.01.007---
Hypoxia22.02.02.003--
Injection site pain08.02.03.010; 12.07.03.0110.000607%-
Laryngospasm22.04.02.002--
Myoclonus17.02.05.0080.000572%-
Pain08.01.08.004--
Respiratory failure14.01.04.003; 22.02.06.002--
Seizure17.12.03.0010.000357%
Snoring22.12.03.025---
Tachycardia02.03.02.0070.000268%-
Vascular pain24.03.02.026---
Vomiting07.01.07.0030.000179%
Procedural nausea07.01.07.005; 12.02.03.003---
Upper airway obstruction22.12.03.032---
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