Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Butorphanol
Drug ID BADD_D00324
Description A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Indications and Usage For the relief of moderate to severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AF01
DrugBank ID DB00611
KEGG ID D03197
MeSH ID D002077
PubChem ID 5361092
TTD Drug ID D0X9RG
NDC Product Code Not Available
Synonyms Butorphanol | 17-(Cyclobutylmethyl)morphinan-3,14-diol | BC-2627 | BC 2627 | BC2627 | Beforal | Butorphanol Tartrate | Moradol | Stadol | Stadol NS | Torbugesic | Apo-Butorphanol | Dolorex
Chemical Information
Molecular Formula C21H29NO2
CAS Registry Number 42408-82-2
SMILES C1CCC2(C3CC4=C(C2(C1)CCN3CC5CCC5)C=C(C=C4)O)O
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Abnormal dreams17.15.02.001; 19.02.03.001--Not Available
Ageusia07.14.03.003; 17.02.07.001--Not Available
Agitation17.02.05.012; 19.06.02.001--
Anxiety19.06.02.002--
Apnoea22.02.01.001--
Arrhythmia02.03.02.001--Not Available
Asthenia08.01.01.001--Not Available
Ataxia08.01.02.004; 17.02.02.001--
Back pain15.03.04.005--
Blood pressure increased13.14.03.005--Not Available
Body temperature increased13.15.01.001--Not Available
Bronchitis11.01.09.001; 22.07.01.001--
Chest pain02.02.02.011; 08.01.08.002; 22.02.08.003--Not Available
Chills08.01.09.001; 15.05.03.016--
Cold sweat08.01.03.024; 23.02.03.002--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Coordination abnormal17.02.02.004--Not Available
Cough22.02.03.001--
Deafness04.02.01.001--Not Available
Death08.04.01.001--
Delusion19.10.01.001--
Depressed level of consciousness17.02.04.002--
Depression19.15.01.001--
Derealisation19.10.02.001--Not Available
Dermatitis23.03.04.002--Not Available
Diplopia06.02.06.002; 17.17.01.005--Not Available
Dizziness02.01.02.004; 17.02.05.003; 24.06.02.007--
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