Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Bacitracin
Drug ID BADD_D00208
Description Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A.[A181952] The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy.[A181952] Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Indications and Usage However, specific activity of bactracin's inhibition of protein disulfide isomerase has been called into question.
Marketing Status Prescription; Discontinued
ATC Code D06AX05; J01XX10; R02AB04
DrugBank ID DB00626
KEGG ID D00128
MeSH ID D001414
PubChem ID 10909430
TTD Drug ID D0M1IO
NDC Product Code 70594-026; 59779-536; 37808-536; 50090-0845; 11673-073; 44231-0004; 39892-0810; 52928-001; 67777-116; 38779-0015; 0574-4022; 55910-536; 30142-536; 61919-116; 41250-844; 72572-025; 68786-218; 54147-0001; 80489-006; 71205-057; 0363-0075; 50090-0846; 44231-0006; 73921-016; 44231-0005; 50090-0815; 76003-0162; 68071-5253; 44231-0007; 75983-005; 36800-536; 55681-218; 45932-0026; 68788-9794; 51551-0301; 68071-4285; 66267-988; 67234-059; 39892-0830; 51552-1315; 68071-2395; 21130-757; 45802-060; 45932-0021; 63187-299; 55154-1950; 63323-329; 0713-0280; 68001-477; 0536-1256; 59428-135; 55500-0002; 59898-720
Synonyms Bacitracin | Altracin | Baci-IM | Baci IM | Zeba-Rx | Zeba Rx | Baci-Rx | Baci Rx | Topitracin | Bacitin | Bacitracin Zinc Complex | Zinc Bacitracin | Bacitracin, Zinc | Bacitracin Zinc | Zinc, Bacitracin | Bacitracine Martinet | Martinet, Bacitracine | Ocu-Tracin | Ocu Tracin | OcuTracin | Ak-Tracin | Ak Tracin | Baciguent
Chemical Information
Molecular Formula C66H103N17O16S
CAS Registry Number 22601-59-8
SMILES CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCCCCC(C(=O)NC(C(=O)N1)CCCN)NC(=O)C (C(C)CC)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C2CSC(=N2)C(C(C)CC)N)CC(=O)N)CC(=O )O)CC3=CN=CN3)CC4=CC=CC=C4
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Albuminuria20.02.01.001--Not Available
Azotaemia20.01.01.001--Not Available
Blood urea increased13.13.01.006--Not Available
Cylindruria20.02.01.004--Not Available
Dermatitis23.03.04.002--Not Available
Injection site pain08.02.03.010; 12.07.03.011--Not Available
Nausea07.01.07.001--
Pain08.01.08.004--
Rash23.03.13.001--Not Available
Vomiting07.01.07.003--
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