Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Antihemophilic factor (recombinant)
Drug ID BADD_D00147
Description Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Indications and Usage For the treatment of hemophilia A, von Willebrand disease and Factor XIII deficiency.
Marketing Status Not Available
ATC Code B02BD02
DrugBank ID DB00025
KEGG ID D05401
MeSH ID C078147
PubChem ID Not Available
TTD Drug ID Not Available
NDC Product Code 0944-3054; 0026-3787; 68982-139; 58394-015; 0026-3828; 68982-143; 58394-025; 0944-3045; 0944-3051; 0944-3047; 0026-3824; 0944-3053; 58394-013; 0026-3826; 68982-151; 68982-153; 0026-3782; 0026-3783; 0944-3046; 58394-023; 0026-3786; 58394-024; 0026-3785; 68982-145; 68982-141; 0026-3822; 68982-147; 0026-3821; 58394-014; 58394-012; 58394-016; 58394-022; 68982-149; 0944-3052
Synonyms F8 protein, human | antihemophilic factor human | factor VIII, human | coagulation factor VIII, human | coagulation factor VIII, procoagulant component (hemophilia A) protein, human | FVIII protein, human | BAY 81-8973 | F8B protein, human | Bioclate | Hemofil | Hemofil M | Hemophil | Hemofil HM | Kogenate FS | Kogenate | Monoclate | Recombinate | xyntha | Kovaltry | octocog alfa | Humate-P
Chemical Information
Molecular Formula Not Available
CAS Registry Number 139076-62-3
SMILES Not Available
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Acoustic stimulation tests abnormal13.07.01.004--Not Available
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Angioedema10.01.05.009; 23.04.01.001--Not Available
Chest discomfort02.02.02.009; 08.01.08.019; 22.02.08.001--Not Available
Chest pain02.02.02.011; 08.01.08.002; 22.02.08.003--Not Available
Chills08.01.09.001; 15.05.03.016--
Cough22.02.03.001--
Cyanosis02.01.02.002; 22.02.02.007; 24.03.01.007--
Dizziness02.01.02.004; 17.02.05.003; 24.06.02.007--
Dyspnoea02.01.03.002; 22.02.01.004--
Ear infection04.03.01.006; 11.01.05.001--Not Available
Epistaxis22.04.03.001; 24.07.01.005--
Erythema23.03.06.001--Not Available
Fatigue08.01.01.002--
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Haematoma24.07.01.001--
Headache17.14.01.001--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypersensitivity10.01.03.003--
Hypotension24.06.03.002--
Injection site reaction08.02.03.014; 12.07.03.015--
Laryngeal oedema10.01.05.003; 22.04.02.001; 23.04.01.005--
Laryngeal pain22.02.05.036--
Loss of consciousness17.02.04.004--Not Available
Malaise08.01.01.003--
Nausea07.01.07.001--
Pain in extremity15.03.04.010--
Pallor08.01.03.032; 23.03.03.031; 24.03.04.001--Not Available
Paraesthesia17.02.06.005--
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