Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Alfentanil hydrochloride
Drug ID BADD_D00068
Description A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Indications and Usage For the management of postoperative pain and the maintenance of general anesthesia.
Marketing Status Prescription
ATC Code N01AH02
DrugBank ID DB00802
KEGG ID D00835
MeSH ID D015760
PubChem ID 64761
TTD Drug ID D0A3ES
NDC Product Code 17478-067; 17478-841
Synonyms Alfentanil | Alfentanyl | Alfentanil Hydrochloride | R-39209 | R 39209 | R39209 | Alfenta | Limifen | Rapifen | Fanaxal
Chemical Information
Molecular Formula C21H33ClN6O3
CAS Registry Number 69049-06-5
SMILES CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCN3C(=O)N(N=N3)CC)COC.Cl
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Apnoea22.02.01.001--
Arrhythmia02.03.02.001--Not Available
Bronchospasm10.01.03.012; 22.03.01.004--
Chest discomfort02.02.02.009; 08.01.08.019; 22.02.08.001--Not Available
Chills08.01.09.001; 15.05.03.016--
Dizziness02.01.02.004; 17.02.05.003; 24.06.02.007--
Euphoric mood19.04.02.006--
Headache17.14.01.001--
Hypercapnia14.01.04.001; 22.02.02.002--Not Available
Hypertension24.08.02.001--
Hypotension24.06.03.002--
Laryngospasm22.04.02.002--
Movement disorder17.01.02.010--Not Available
Muscle rigidity15.05.04.001; 17.05.02.005--Not Available
Myoclonus17.02.05.008--Not Available
Nausea07.01.07.001--
Pain08.01.08.004--
Pruritus23.03.12.001--
Sedation17.02.04.005--Not Available
Somnolence17.02.04.006; 19.02.05.003--
Tachycardia02.03.02.007--Not Available
Urticaria10.01.06.001; 23.04.02.001--
Vision blurred06.02.06.007; 17.17.01.010--
Vomiting07.01.07.003--
Confusion postoperative12.02.04.001; 17.02.03.004; 19.13.01.004--Not Available
Postoperative respiratory distress12.02.07.001; 22.02.06.006--Not Available
Nuchal rigidity15.05.04.005; 17.05.02.006--Not Available
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