Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Giant cell arteritis
ADR ID BADD_A09976
ADR Hierarchy
24      Vascular disorders
24.12      Vascular infections and inflammations
24.12.02      Arterial infections and inflammations
24.12.02.003      Giant cell arteritis
17      Nervous system disorders
17.08      Central nervous system vascular disorders
17.08.02      Central nervous system vascular disorders NEC
17.08.02.033      Giant cell arteritis
06      Eye disorders
06.07      Ocular haemorrhages and vascular disorders NEC
06.07.02      Ocular bleeding and vascular disorders NEC
06.07.02.010      Giant cell arteritis
10      Immune system disorders
10.02      Immune disorders NEC
10.02.02      Vasculitides
10.02.02.032      Giant cell arteritis
Description A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed) [MeSH]
MedDRA Code 10018250
MeSH ID D013700; D020293
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cranial arteritis | Giant cell arteritis | Granulomatous arteritis | Horton's arteritis | Horton's disease | Temporal arteritis | Giant Cell Arteritis | Arteritides, Giant Cell | Arteritis, Giant Cell | Giant Cell Arteritides | Arteritis, Giant Cell, Horton's | Horton's Giant Cell Arteritis | Horton Disease | Horton Giant Cell Arteritis | Horton's Disease | Hortons Disease | Arteritis, Giant Cell, Horton | Giant Cell Arteritis, Horton | Temporal Arteritis | Arteritides, Temporal | Temporal Arteritides | Arteritis, Temporal | Juvenile Temporal Arteritis | Arteritides, Juvenile Temporal | Arteritis, Juvenile Temporal | Juvenile Temporal Arteritides | Temporal Arteritides, Juvenile | Temporal Arteritis, Juvenile | Aortic Arteritis, Giant Cell | Giant Cell Aortitis, Horton's | Giant Cell Aortitis | Aortitis, Giant Cell | Aortitides, Giant Cell | Giant Cell Aortitides | Giant Cell Aortic Arteritis | Cranial Arteritis | Arteritides, Cranial | Arteritis, Cranial | Cranial Arteritides
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000132%
BADD_D00151Apixaban0.000108%
BADD_D00156Apremilast0.000772%
BADD_D00563Dabigatran0.000245%
BADD_D01253Lenalidomide0.000651%
BADD_D01405Methadone0.000265%
BADD_D01418Methotrexate--
BADD_D01476Mirtazapine0.000080%
BADD_D01567Nilotinib0.000224%
BADD_D01831Prednisolone0.000035%
BADD_D01834Prednisone0.000009%
BADD_D02098Sumatriptan--
BADD_D02099Sumatriptan succinate--
BADD_D02329Valproic acid0.000100%
BADD_D02392Zoledronic acid0.005726%
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