Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Lateral medullary syndrome
ADR ID BADD_A07351
ADR Hierarchy
17      Nervous system disorders
17.08      Central nervous system vascular disorders
17.08.01      Central nervous system haemorrhages and cerebrovascular accidents
17.08.01.055      Lateral medullary syndrome
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.06      Cerebrovascular and spinal necrosis and vascular insufficiency
24.04.06.038      Lateral medullary syndrome
Description INFARCTION of the dorsolateral aspect of MEDULLA OBLONGATA in the BRAIN STEM. It is caused by occlusion of the VERTEBRAL ARTERY and/or the posterior inferior cerebellar artery. Clinical manifestations vary with the size of infarction, but may include loss of pain and temperature sensation in the ipsilateral face and contralateral body below the chin; ipsilateral HORNER SYNDROME; ipsilateral ATAXIA; DYSARTHRIA; VERTIGO; nausea, hiccup; dysphagia; and VOCAL CORD PARALYSIS. (From Adams et al., Principles of Neurology, 6th ed, p801) [MeSH]
MedDRA Code 10024033
MeSH ID D014854
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Lateral medullary syndrome | Posterior inferior cerebellar artery occlusion | Wallenberg syndrome | Lateral Medullary Syndrome | Lateral Medullary Syndromes | Syndromes, Lateral Medullary | Posterior Inferior Cerebellar Artery Syndrome | Wallenberg's Syndrome | Wallenbergs Syndrome | Vieseaux-Wallenberg Syndrome | Syndrome, Vieseaux-Wallenberg | Vieseaux Wallenberg Syndrome | Wallenberg Syndrome | Syndrome, Wallenberg | Dorsolateral Medullary Syndrome | Medullary Syndrome, Dorsolateral | Lateral Bulbar Syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01275Levofloxacin0.000127%
BADD_D01470Minocycline0.000236%
BADD_D01954Rivaroxaban0.000095%
BADD_D02165Teriflunomide0.000241%
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