Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Pulmonary arterial hypertension
ADR ID BADD_A06275
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.06      Pulmonary vascular disorders
22.06.01      Pulmonary hypertensions
22.06.01.002      Pulmonary arterial hypertension
24      Vascular disorders
24.08      Vascular hypertensive disorders
24.08.03      Pulmonary hypertensions
24.08.03.003      Pulmonary arterial hypertension
Description Familial or idiopathic hypertension in the PULMONARY CIRCULATION which is not secondary to other disease. [MeSH]
MedDRA Code 10064911
MeSH ID D065627
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Primary pulmonary hypertension | Pulmonary hypertension primary | Associated with (APAH) | Idiopathic (IPAH) | Pulmonary arterial hypertension | Associated with pulmonary arterial hypertension | Idiopathic pulmonary arterial hypertension | Secondary pulmonary arterial hypertension | Pulmonary arterial hypertension WHO functional class III | Pulmonary arterial hypertension WHO functional class IV | Pulmonary arterial hypertension WHO functional class I | Pulmonary arterial hypertension WHO functional class II | Toxic pulmonary arterial hypertension | Drug and toxin-induced pulmonary arterial hypertension | Familial Primary Pulmonary Hypertension | Heritable Pulmonary Arterial Hypertension | Pulmonary Hypertension, Primary, Fenfluramine-Associated | Pulmonary Hypertension, Primary, Dexfenfluramine-Associated | Idiopathic Pulmonary Arterial Hypertension | Primary Pulmonary Hypertension | Hypertension, Primary Pulmonary | Hypertensions, Primary Pulmonary | Primary Pulmonary Hypertensions | Pulmonary Hypertension, Primary | Pulmonary Hypertensions, Primary | Idiopathic Pulmonary Hypertension | Hypertension, Idiopathic Pulmonary | Hypertensions, Idiopathic Pulmonary | Idiopathic Pulmonary Hypertensions | Pulmonary Hypertension, Idiopathic | Pulmonary Hypertensions, Idiopathic | Pulmonary Hypertension, Primary, 1 | Pulmonary Hypertension, Primary, 1, With Hereditary Hemorrhagic Telangiectasia | Pph1 With Hht | Hht, Pph1 With | Hhts, Pph1 With | Pph1 With Hhts | With Hht, Pph1 | With Hhts, Pph1
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02018Sildenafil0.001149%
BADD_D02019Sildenafil citrate--
BADD_D02053Sofosbuvir0.001270%
BADD_D02106Tadalafil0.001893%
BADD_D02107Tafamidis0.000808%
BADD_D02192Thalidomide0.000772%
BADD_D02268Treprostinil0.012271%
BADD_D02470Nintedanib0.000336%
BADD_D02471Oxygen0.001239%
BADD_D02504Lorlatinib0.000280%
BADD_D02509Brigatinib0.000168%
BADD_D02539Calcium0.000391%
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