Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Drug resistance
ADR ID BADD_A05694
ADR Hierarchy
08      General disorders and administration site conditions
08.06      Therapeutic and nontherapeutic effects (excl toxicity)
08.06.01      Therapeutic and nontherapeutic responses
08.06.01.005      Drug resistance
Description Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration. [MeSH]
MedDRA Code 10059866
MeSH ID D004351
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Drug resistance | Drug Resistance | Resistance, Drug
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02504Lorlatinib0.000246%
BADD_D02509Brigatinib0.000470%
BADD_D02524Ivosidenib0.000168%
BADD_D02526Larotrectinib0.000548%
BADD_D02541Cefiderocol0.000131%
BADD_D02571Maribavir0.002992%
BADD_D02577Oseltamivir acid0.003842%
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ADReCS-Target
ADR Term Drug Name Target