Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cluster headache
ADR ID BADD_A05648
ADR Hierarchy
17      Nervous system disorders
17.14      Headaches
17.14.01      Headaches NEC
17.14.01.003      Cluster headache
Description A primary headache disorder that is characterized by severe, strictly unilateral PAIN which is orbital, supraorbital, temporal or in any combination of these sites, lasting 15-180 min. occurring 1 to 8 times a day. The attacks are associated with one or more of the following, all of which are ipsilateral: conjunctival injection, lacrimation, nasal congestion, rhinorrhea, facial SWEATING, eyelid EDEMA, and miosis. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1) [MeSH]
MedDRA Code 10059133
MeSH ID D003027
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cluster headaches | Harris's migrainous neuralgia | Headache histamine | Headache vasomotor | Headaches cluster | Horton's headache | Cluster headache | Episodic cluster headache | Chronic cluster headache | Cluster Headache | Cluster Headaches | Headaches, Cluster | Ciliary Neuralgia | Ciliary Neuralgias | Neuralgia, Ciliary | Neuralgias, Ciliary | Cluster Headache Syndrome | Cluster Headache Syndromes | Headache Syndrome, Cluster | Headache Syndromes, Cluster | Syndrome, Cluster Headache | Syndromes, Cluster Headache | Neuralgic Migraine | Migraine, Neuralgic | Migraines, Neuralgic | Neuralgic Migraines | Histamine Cephalgia | Cephalgia, Histamine | Cephalgias, Histamine | Histamine Cephalgias | Horton Syndrome | Syndrome, Horton | Horton's Syndrome | Hortons Syndrome | Syndrome, Horton's | Chronic Cluster Headache | Chronic Cluster Headaches | Cluster Headache, Chronic | Cluster Headaches, Chronic | Headache, Chronic Cluster | Headaches, Chronic Cluster | Headache, Cluster | Episodic Cluster Headache | Cluster Headache, Episodic | Cluster Headaches, Episodic | Episodic Cluster Headaches | Headache, Episodic Cluster | Headaches, Episodic Cluster | Atypical Cluster Headache | Atypical Cluster Headaches | Cluster Headache, Atypical | Cluster Headaches, Atypical | Headache, Atypical Cluster | Headaches, Atypical Cluster
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00156Apremilast0.002580%
BADD_D00356Carbamazepine0.000186%
BADD_D00501Clonazepam0.000030%
BADD_D00680Dimethyl fumarate0.001360%
BADD_D00898Finasteride0.000067%
BADD_D01285Levothyroxine0.000005%
BADD_D01401Metformin0.000024%
BADD_D01982Salmeterol xinafoate--
BADD_D02098Sumatriptan--
BADD_D02099Sumatriptan succinate--
BADD_D02236Tofacitinib0.000530%
BADD_D02464Fingolimod0.000772%
BADD_D02471Oxygen0.001239%
BADD_D02503Telotristat ethyl-
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