Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hypogonadism
ADR ID BADD_A05576
ADR Hierarchy
05      Endocrine disorders
05.05      Endocrine disorders of gonadal function
05.05.04      Endocrine abnormalities of gonadal function NEC
05.05.04.002      Hypogonadism
21      Reproductive system and breast disorders
21.03      Sexual function and fertility disorders
21.03.02      Sexual function and fertility disorders NEC
21.03.02.010      Hypogonadism
Description Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism). [MeSH]
MedDRA Code 10058359
MeSH ID D007006
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Hypogonadism | Gonadal insufficiency | Impaired gonadal steroidogenesis | Hypogonadism, Isolated Hypogonadotropic | Hypogonadotropic Hypogonadism | Hypogonadism, Hypogonadotropic | Hypergonadotropic Hypogonadism | Hypogonadism, Hypergonadotropic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000044%
BADD_D00315Buserelin acetate--
BADD_D00318Busulfan--
BADD_D00879Fentanyl--
BADD_D00898Finasteride0.004539%
BADD_D00932Fluoxetine0.000030%
BADD_D01096Hydromorphone--
BADD_D01261Leuprolide monoacetate--
BADD_D01372Megestrol acetate0.001107%
BADD_D01405Methadone--
BADD_D01406Methadone hydrochloride--
BADD_D01498Morphine--
BADD_D01595Octreotide acetate--
BADD_D01645Oxycodone--
BADD_D01735Pergolide--
BADD_D01736Pergolide mesylate--
BADD_D01831Prednisolone0.000035%
BADD_D01951Risperidone0.000388%
BADD_D02150Temozolomide0.000112%
BADD_D02170Testosterone0.000382%
BADD_D02174Testosterone undecanoate--
BADD_D02203Thiotepa--
BADD_D02392Zoledronic acid--
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