Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Autoimmune thyroiditis
ADR ID BADD_A04784
ADR Hierarchy
05      Endocrine disorders
05.02      Thyroid gland disorders
05.02.04      Acute and chronic thyroiditis
05.02.04.002      Autoimmune thyroiditis
10      Immune system disorders
10.04      Autoimmune disorders
10.04.08      Endocrine autoimmune disorders
10.04.08.006      Autoimmune thyroiditis
Description Inflammatory disease of the THYROID GLAND due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-CELLS and thyroid AUTOANTIBODIES. The clinical signs can range from HYPOTHYROIDISM to THYROTOXICOSIS depending on the type of autoimmune thyroiditis. [MeSH]
MedDRA Code 10049046
MeSH ID D013967; D050031; D013967; D013967; D013967
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Chronic lymphocytic thyroiditis | Hashimoto's disease | Hashimoto's thyroiditis | Lymphocytic thyroiditis | Autoimmune thyroiditis | Thyroiditis, Autoimmune | Autoimmune Thyroiditides | Thyroiditides, Autoimmune | Autoimmune Thyroiditis | Thyroiditis, Lymphocytic | Lymphocytic Thyroiditides | Lymphocytic Thyroiditis | Thyroiditides, Lymphocytic | Thyroiditis, Lymphomatous | Lymphomatous Thyroiditides | Lymphomatous Thyroiditis | Thyroiditides, Lymphomatous
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000066%
BADD_D00479Cladribine0.000642%
BADD_D00589Dasatinib0.000168%
BADD_D00680Dimethyl fumarate0.000880%
BADD_D00788Epoprostenol0.000123%
BADD_D00979Furosemide0.000014%
BADD_D01213Isotretinoin0.001029%
BADD_D01265Levetiracetam0.000119%
BADD_D01281Levonorgestrel0.002837%
BADD_D01285Levothyroxine0.000044%
BADD_D01431Methylphenidate0.000041%
BADD_D01470Minocycline0.000767%
BADD_D01484Modafinil0.000412%
BADD_D01567Nilotinib0.000828%
BADD_D01653Paclitaxel0.000168%
BADD_D01765Phenytoin0.000669%
BADD_D01933Ribavirin0.019779%
BADD_D01951Risperidone0.000121%
BADD_D02047Sodium oxybate0.000268%
BADD_D02100Sunitinib0.000504%
BADD_D02165Teriflunomide0.000482%
BADD_D02236Tofacitinib0.000603%
BADD_D02264Trastuzumab--
BADD_D02392Zoledronic acid--
BADD_D02504Lorlatinib0.000168%
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