Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Rectal cancer
ADR ID BADD_A03710
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.13      Gastrointestinal neoplasms malignant and unspecified
16.13.01      Colorectal neoplasms malignant
16.13.01.003      Rectal cancer
07      Gastrointestinal disorders
07.21      Malignant and unspecified neoplasms gastrointestinal NEC
07.21.05      Malignant anorectal neoplasms
07.21.05.002      Rectal cancer
Description Tumors or cancer of the RECTUM. [MeSH]
MedDRA Code 10038038
MeSH ID D012004
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Carcinoma of rectum | Carcinoma rectum | Carcinoma rectum stage unspecified | Malignant neoplasm of rectum | Malignant neoplasm of rectum stage unspecified | Rectal cancer | Rectal cancer NOS | Rectal carcinoma | Rectal carcinoma stage unspecified | Scirrhous carcinoma of the rectum stage unspecified | Squamous cell carcinoma of rectum | HPV positive rectal squamous cell carcinoma | Rectal Neoplasms | Neoplasm, Rectal | Rectal Neoplasm | Rectum Neoplasms | Neoplasm, Rectum | Rectum Neoplasm | Rectal Tumors | Rectal Tumor | Tumor, Rectal | Neoplasms, Rectal | Cancer of Rectum | Rectum Cancers | Rectal Cancer | Cancer, Rectal | Rectal Cancers | Rectum Cancer | Cancer, Rectum | Cancer of the Rectum
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00151Apixaban0.000347%
BADD_D00195Azathioprine--
BADD_D00344Canagliflozin0.000180%
BADD_D00349Capecitabine0.000694%
BADD_D00504Clopidogrel0.000053%
BADD_D00511Clozapine--
BADD_D00563Dabigatran0.001713%
BADD_D00589Dasatinib0.000112%
BADD_D00680Dimethyl fumarate0.000800%
BADD_D00765Empagliflozin0.000091%
BADD_D00774Entecavir0.003269%
BADD_D00775Enzalutamide0.000501%
BADD_D00858Everolimus0.000229%
BADD_D00898Finasteride0.000045%
BADD_D01119Ibrutinib0.000336%
BADD_D01136Imatinib0.000448%
BADD_D01195Irinotecan0.000929%
BADD_D01258Leucovorin0.001239%
BADD_D01260Leuprolide acetate--
BADD_D01281Levonorgestrel--
BADD_D01392Mercaptopurine--
BADD_D01418Methotrexate--
BADD_D01567Nilotinib0.000168%
BADD_D01602Olmesartan0.000105%
BADD_D01831Prednisolone0.000052%
BADD_D01834Prednisone--
BADD_D01835Pregabalin0.000104%
BADD_D01913Ranitidine0.000050%
BADD_D01922Regorafenib0.002350%
BADD_D01933Ribavirin0.003956%
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