Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Peroneal nerve palsy
ADR ID BADD_A03386
ADR Hierarchy
17      Nervous system disorders
17.09      Peripheral neuropathies
17.09.02      Mononeuropathies
17.09.02.003      Peroneal nerve palsy
Description Disease involving the common PERONEAL NERVE or its branches, the deep and superficial peroneal nerves. Lesions of the deep peroneal nerve are associated with PARALYSIS of dorsiflexion of the ankle and toes and loss of sensation from the web space between the first and second toe. Lesions of the superficial peroneal nerve result in weakness or paralysis of the peroneal muscles (which evert the foot) and loss of sensation over the dorsal and lateral surface of the leg. Traumatic injury to the common peroneal nerve near the head of the FIBULA is a relatively common cause of this condition. (From Joynt, Clinical Neurology, 1995, Ch51, p31) [MeSH]
MedDRA Code 10034701
MeSH ID D020427
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Foot drop | Footdrop | Palsy peroneal | Paralysis peroneal | Peroneal nerve palsy | Peroneal Neuropathies | Neuropathy, Peroneal | Peroneal Neuropathy | Peroneal Mononeuropathies | Mononeuropathy, Peroneal | Peroneal Mononeuropathy | Fibular Nerve Diseases | Fibular Nerve Disease | Nerve Disease, Fibular | Peroneal Nerve Diseases | Peroneal Nerve Disease | Fibular Neuropathy | Fibular Neuropathies | Neuropathies, Fibular | Neuropathy, Fibular | Neuropathy, Common Peroneal | Common Peroneal Neuropathies | Common Peroneal Neuropathy | Lateral Popliteal Neuropathy | Lateral Popliteal Neuropathies | Neuropathy, Lateral Popliteal | Popliteal Neuropathy, Lateral | External Popliteal Neuropathy | External Popliteal Neuropathies | Neuropathy, External Popliteal | Popliteal Neuropathy, External | Common Peroneal Nerve Entrapment | Neuropathy, Superficial Peroneal | Peroneal Neuropathy, Superficial | Superficial Peroneal Neuropathies | Superficial Peroneal Neuropathy | Peroneal Nerve Paralysis | Nerve Paralysis, Peroneal | Paralysis, Peroneal Nerve | Peroneal Nerve Paralyses | Peroneal Palsy | Palsy, Peroneal | Peroneal Palsies | Foot Drop | Foot Drops | Peroneal Nerve Entrapment | Entrapment, Peroneal Nerve | Nerve Entrapment, Peroneal | Peroneal Nerve Entrapments | Neuropathy, Deep Peroneal | Deep Peroneal Neuropathies | Deep Peroneal Neuropathy | Peroneal Neuropathy, Deep
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01633Oxaliplatin0.000246%
BADD_D01653Paclitaxel0.000224%
BADD_D01687Pazopanib0.000381%
BADD_D01835Pregabalin0.000244%
BADD_D01846Procarbazine--
BADD_D01847Procarbazine hydrochloride--
BADD_D01909Ramipril--
BADD_D01916Rasagiline mesylate--
BADD_D01942Riluzole0.000808%
BADD_D02010Sertraline0.000019%
BADD_D02100Sunitinib0.000112%
BADD_D02105Tacrolimus0.001396%
BADD_D02165Teriflunomide0.003882%
BADD_D02192Thalidomide--
BADD_D02194Thallous chloride tl-201--
BADD_D02236Tofacitinib0.001423%
BADD_D02329Valproic acid0.000100%
BADD_D02360Vincristine--
BADD_D02373Warfarin0.000042%
BADD_D02375Water--
BADD_D02464Fingolimod0.006655%
BADD_D02511Siponimod0.001350%
BADD_D02580Ozanimod0.000820%
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