Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Muscle atrophy
ADR ID BADD_A02876
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.03      Muscle related signs and symptoms NEC
15.05.03.003      Muscle atrophy
17      Nervous system disorders
17.05      Neuromuscular disorders
17.05.03      Neuromuscular disorders NEC
17.05.03.004      Muscle atrophy
Description Derangement in size and number of muscle fibers occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessness, malnutrition, and particularly in denervation. [MeSH]
MedDRA Code 10028289
MeSH ID D009133
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Atrophy muscle | Atrophy skeletal muscle | Degeneration muscle | Disuse muscle atrophy | Muscle atrophy | Muscle degeneration | Muscle fibrosis atrophy | Muscle fibrous atrophy | Muscle wasting | Muscle wasting (disuse) | Muscular wasting and disuse atrophy, not elsewhere classified | Myopenia | Localized muscle atrophy | Localised muscle atrophy | Muscular Atrophy | Atrophies, Muscular | Atrophy, Muscular | Muscular Atrophies | Atrophy, Muscle | Atrophies, Muscle | Muscle Atrophies | Muscle Atrophy | Neurogenic Muscular Atrophy | Atrophies, Neurogenic Muscular | Atrophy, Neurogenic Muscular | Muscular Atrophies, Neurogenic | Muscular Atrophy, Neurogenic | Neurogenic Muscular Atrophies | Neurotrophic Muscular Atrophy | Atrophies, Neurotrophic Muscular | Atrophy, Neurotrophic Muscular | Muscular Atrophies, Neurotrophic | Muscular Atrophy, Neurotrophic | Neurotrophic Muscular Atrophies
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00775Enzalutamide0.001635%
BADD_D00864Ezetimibe0.000157%
BADD_D00879Fentanyl--
BADD_D00880Fentanyl citrate--
BADD_D00898Finasteride0.002076%
BADD_D00917Fludrocortisone--
BADD_D00978Fulvestrant0.001135%
BADD_D00981Gabapentin0.000037%
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01083Hydrochlorothiazide0.000010%
BADD_D01104Hydroxychloroquine sulfate--
BADD_D01119Ibrutinib0.000168%
BADD_D01136Imatinib0.000168%
BADD_D01167Interferon alfa-2b--
BADD_D01194Irbesartan--
BADD_D01197Iron--
BADD_D01242Lamivudine0.002024%
BADD_D01243Lamotrigine--
BADD_D01257Letrozole0.000395%
BADD_D01260Leuprolide acetate0.010612%
BADD_D01261Leuprolide monoacetate--
BADD_D01275Levofloxacin0.000464%
BADD_D01285Levothyroxine0.000023%
BADD_D01311Lomitapide0.000073%
BADD_D01318Lorazepam0.000062%
BADD_D01352Maraviroc--
BADD_D01376Melphalan--
BADD_D01401Metformin0.000025%
BADD_D01431Methylphenidate--
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