Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hypersplenism
ADR ID BADD_A02148
ADR Hierarchy
01      Blood and lymphatic system disorders
01.09      Spleen, lymphatic and reticuloendothelial system disorders
01.09.02      Spleen disorders
01.09.02.002      Hypersplenism
Description Condition characterized by splenomegaly, some reduction in the number of circulating blood cells in the presence of a normal or hyperactive bone marrow, and the potential for reversal by splenectomy. [MeSH]
MedDRA Code 10020769
MeSH ID D006971
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Hypersplenism | Hypersplenism acquired | Splenic sequestration | Splenic sequestration crisis | Anemia, Splenic | Anemias, Splenic | Splenic Anemia | Splenic Anemias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00511Clozapine0.005503%
BADD_D00594Deferasirox0.002478%
BADD_D00595Deferiprone--
BADD_D00788Epoprostenol0.000304%
BADD_D00789Epoprostenol sodium--
BADD_D01096Hydromorphone0.000185%
BADD_D01110Hydroxyurea0.000168%
BADD_D01392Mercaptopurine0.001041%
BADD_D01905Raltegravir0.001648%
BADD_D01933Ribavirin0.005934%
BADD_D01978Ruxolitinib0.000137%
BADD_D02411Voxelotor-
BADD_D02464Fingolimod0.000362%
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