Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Fibrosis
ADR ID BADD_A01656
ADR Hierarchy
08      General disorders and administration site conditions
08.03      Tissue disorders NEC
08.03.01      Fibrosis NEC
08.03.01.001      Fibrosis
Description Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury. [MeSH]
MedDRA Code 10016642
MeSH ID D005355
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Fibrosis | Fibrosis NOS | Lymphedema related fibrosis | Lymphoedema related fibrosis | Fibroses | Cirrhosis
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00914Fludarabine--
BADD_D00915Fludarabine phosphate--
BADD_D00931Fluorouracil--
BADD_D00941Flurbiprofen--
BADD_D00942Flurbiprofen sodium--
BADD_D00978Fulvestrant0.000734%
BADD_D00985Gadodiamide0.017783%
BADD_D01110Hydroxyurea0.000112%
BADD_D01136Imatinib0.000280%
BADD_D01197Iron--
BADD_D01213Isotretinoin0.000695%
BADD_D01242Lamivudine0.003542%
BADD_D01304Lithium cation0.000192%
BADD_D01313Lomustine--
BADD_D01336Macitentan0.000120%
BADD_D01356Mecamylamine--
BADD_D01384Meperidine--
BADD_D01418Methotrexate0.000171%
BADD_D01440Methysergide maleate--
BADD_D01478Mitomycin0.000112%
BADD_D01496Montelukast0.000022%
BADD_D01563Nicotinate--
BADD_D01576Nitrofurantoin--
BADD_D01592Obeticholic acid0.001042%
BADD_D01602Olmesartan0.000105%
BADD_D01633Oxaliplatin0.000112%
BADD_D01653Paclitaxel--
BADD_D01765Phenytoin--
BADD_D01783Pirfenidone0.000772%
BADD_D01831Prednisolone0.000122%
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