Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Demyelinating disorders
ADR ID BADD_A01193
ADR Hierarchy
17      Nervous system disorders
17.16      Demyelinating disorders
Description Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system. | The first region-restricted episode of CNS inflammatory demyelination in a patient. It is usually characterized by an acute monosymptomatic presentation of the optic nerves, brainstem, or spinal cord. It may not reoccur (isolated), or it may progress to MULTIPLE SCLEROSIS. [MeSH]
MedDRA Code 10012303
MeSH ID D003711
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Demyelinating Diseases | Demyelinating Disease | Demyelinating Disorders | Demyelinating Disorder | Demyelination | Demyelinations | Clinically Isolated Syndrome, CNS Demyelinating | Clinically Isolated CNS Demyelinating Syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01588Nortriptyline--
BADD_D01596Ofatumumab--
BADD_D01601Olaparib0.000112%
BADD_D01629Osimertinib0.000224%
BADD_D01633Oxaliplatin0.001175%
BADD_D01653Paclitaxel0.000280%
BADD_D01668Pantoprazole0.000016%
BADD_D01679Paroxetine--
BADD_D01741Perindoprilat--
BADD_D01765Phenytoin0.000191%
BADD_D01775Pinaverium bromide--
BADD_D01831Prednisolone0.000105%
BADD_D01834Prednisone0.000009%
BADD_D01835Pregabalin--
BADD_D01909Ramipril--
BADD_D01915Ranolazine0.000284%
BADD_D01933Ribavirin0.003956%
BADD_D01953Rituximab--
BADD_D01989Saquinavir mesylate--
BADD_D02010Sertraline0.000019%
BADD_D02028Sirolimus--
BADD_D02095Sulfur colloid--
BADD_D02100Sunitinib0.000112%
BADD_D02105Tacrolimus0.005198%
BADD_D02150Temozolomide0.000112%
BADD_D02160Terbinafine0.000298%
BADD_D02165Teriflunomide0.227321%
BADD_D02192Thalidomide--
BADD_D02227Tipranavir disodium--
BADD_D02230Tizanidine0.000052%
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