Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Demyelinating disorders
ADR ID BADD_A01193
ADR Hierarchy
17      Nervous system disorders
17.16      Demyelinating disorders
Description Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system. | The first region-restricted episode of CNS inflammatory demyelination in a patient. It is usually characterized by an acute monosymptomatic presentation of the optic nerves, brainstem, or spinal cord. It may not reoccur (isolated), or it may progress to MULTIPLE SCLEROSIS. [MeSH]
MedDRA Code 10012303
MeSH ID D003711
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Demyelinating Diseases | Demyelinating Disease | Demyelinating Disorders | Demyelinating Disorder | Demyelination | Demyelinations | Clinically Isolated Syndrome, CNS Demyelinating | Clinically Isolated CNS Demyelinating Syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01136Imatinib0.000672%
BADD_D01142Imiquimod--
BADD_D01149Indapamide0.000754%
BADD_D01186Ioversol0.019206%
BADD_D01204Isoniazid0.005560%
BADD_D01217Itraconazole0.002672%
BADD_D01240Lactulose0.000268%
BADD_D01243Lamotrigine--
BADD_D01265Levetiracetam0.000437%
BADD_D01275Levofloxacin0.000253%
BADD_D01285Levothyroxine--
BADD_D01300Lisinopril0.000005%
BADD_D01304Lithium cation0.000384%
BADD_D01318Lorazepam--
BADD_D01366Medroxyprogesterone acetate0.000119%
BADD_D01401Metformin0.000005%
BADD_D01418Methotrexate0.000171%
BADD_D01433Methylprednisolone0.000112%
BADD_D01445Metoprolol--
BADD_D01449Metronidazole0.000026%
BADD_D01475Mirabegron--
BADD_D01476Mirtazapine0.000160%
BADD_D01480Mitoxantrone0.000280%
BADD_D01484Modafinil0.000823%
BADD_D01496Montelukast0.000015%
BADD_D01507Mycophenolate mofetil--
BADD_D01508Mycophenolic acid--
BADD_D01549Nelarabine--
BADD_D01567Nilotinib0.000336%
BADD_D01580Nitrous oxide0.000536%
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