Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cholinergic syndrome
ADR ID BADD_A00909
ADR Hierarchy
17      Nervous system disorders
17.05      Neuromuscular disorders
17.05.01      Autonomic nervous system disorders
17.05.01.002      Cholinergic syndrome
Description Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of ACETYLCHOLINE, and drugs that affect the survival of cholinergic neurons. The term cholinergic agents is sometimes still used in the narrower sense of MUSCARINIC AGONISTS, although most modern texts discourage that usage. [MeSH]
MedDRA Code 10008674
MeSH ID D018678
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cholinergic syndrome | Muscarinic action | Muscarinic effects | Nicotinic effects | Parasympathomimetic syndrome | Syndrome cholinergic | Syndrome parasympathomimetic | Vagotonia | Cholinergic crisis | Cholinergic Agents | Agents, Cholinergic | Cholinergics | Acetylcholine Agents | Agents, Acetylcholine | Cholinergic Drugs | Drugs, Cholinergic | Cholinomimetics | Muscarinic Agents | Agents, Muscarinic | Muscarinics | Nicotinic Agents | Agents, Nicotinic | Nicotinic Effect | Effect, Nicotinic | Nicotinic Effects | Effects, Nicotinic | Cholinergic Effect | Effect, Cholinergic | Cholinergic Effects | Effects, Cholinergic | Muscarinic Effect | Effect, Muscarinic | Muscarinic Effects | Effects, Muscarinic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00364Carboplatin0.000280%
BADD_D00424Cevimeline--
BADD_D00425Cevimeline hydrochloride--
BADD_D00499Clomipramine--
BADD_D00500Clomipramine hydrochloride--
BADD_D00511Clozapine--
BADD_D00706Donepezil0.000916%
BADD_D00931Fluorouracil0.000276%
BADD_D00932Fluoxetine0.000030%
BADD_D01195Irinotecan0.000224%
BADD_D01196Irinotecan hydrochloride--
BADD_D01403Methacholine--
BADD_D01405Methadone0.000265%
BADD_D01442Metoclopramide0.000196%
BADD_D01599Olanzapine0.000210%
BADD_D01633Oxaliplatin0.000280%
BADD_D01771Pilocarpine hydrochloride0.001486%
BADD_D01824Pravastatin0.000017%
BADD_D01881Pyridostigmine0.006375%
BADD_D01951Risperidone--
BADD_D01955Rivastigmine0.002439%
BADD_D02104Tacrine hydrochloride--
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