Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Angiocentric lymphoma
ADR ID BADD_A00230
ADR Hierarchy
01      Blood and lymphatic system disorders
01.11      Lymphomas non-Hodgkin's T-cell
01.11.04      Angiocentric lymphomas
01.11.04.002      Angiocentric lymphoma
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.17      Lymphomas non-Hodgkin's T-cell
16.17.04      Angiocentric lymphomas
16.17.04.002      Angiocentric lymphoma
Description A condition that is characterized by inflammation, ulceration, and perforation of the nose and the PALATE with progressive destruction of midline facial structures. This syndrome can be manifested in several diseases including the nasal type of EXTRANODAL NK-T-CELL LYMPHOMA and GRANULOMATOSIS WITH POLYANGIITIS. | A condition that is characterized by multiple sites of lymphoid infiltration, often with an aggressive, necrotizing lesion of the upper airway. The term was used as a synonym for lethal midline granuloma. [MeSH]
MedDRA Code 10002411
MeSH ID D006103; D008230
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Angiocentric immunoproliferative lesion grade 2 | Angiocentric immunoproliferative lesion grade 3 | Angiocentric lymphoma | Angiocentric lymphoma NOS | Diffuse large cell lymphoma (Angiocentric lymphoma) (Working Formulation) | Diffuse mixed small and large cell lymphoma (Angiocentric lymphoma) (Working Formulation) | Diffuse small cleaved cell lymphoma (Angiocentric lymphoma) (Working Formulation) | Idiopathic midline granuloma | Large cell immunoblastic lymphoma (Angiocentric lymphoma) (Working Formulation) | Lethal midline granuloma | Lymphomatoid granulomatosis | Midline malignant reticulosis | Nasal T-cell lymphoma | Polymorphic reticulosis | Extranodal NK/T-cell lymphoma, nasal type | Extranodal NK/T-cell lymphoma | Granuloma, Lethal Midline | Granulomas, Lethal Midline | Lethal Midline Granulomas | Midline Granuloma, Lethal | Midline Granulomas, Lethal | Lethal Midline Granuloma | Granuloma Gangraenescens | Polymorphic Reticulosis | Polymorphic Reticuloses | Reticuloses, Polymorphic | Reticulosis, Polymorphic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00195Azathioprine0.001410%
BADD_D01136Imatinib0.000112%
BADD_D01392Mercaptopurine0.002082%
BADD_D01418Methotrexate0.001308%
BADD_D01773Pimecrolimus--
BADD_D01799Ponatinib0.000168%
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