Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cephalothin
Drug ID BADD_D02617
Description Cefalotin is a cephalosporin antibiotic.
Indications and Usage Used to prevent infection during surgery and to treat many kinds of infections of the blood, bone or joints, respiratory tract, skin, and urinary tract.
Marketing Status approved; investigational; vet_approved
ATC Code J01DB03
DrugBank ID DB00456
KEGG ID D07635
MeSH ID D002512
PubChem ID 6024
TTD Drug ID D01PLN
NDC Product Code Not Available
UNII R72LW146E6
Synonyms Cephalothin | Cefalotin | Ceftina | Cefalotina Normon | Seffin | Keflin | Sodium Cephalothin | Cephalothin, Sodium | Cephalothin Monosodium Salt | Monosodium Salt, Cephalothin | Salt, Cephalothin Monosodium | Cefalotina Sodica Spaly
Chemical Information
Molecular Formula C16H16N2O6S2
CAS Registry Number 153-61-7
SMILES CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CC3=CC=CS3)SC1)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Deafness04.02.01.001---
Diarrhoea07.02.01.001--
Erythema23.03.06.001---
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Leukopenia01.02.02.001---
Oedema08.01.07.006; 14.05.06.010---
Phlebitis12.02.01.002; 24.12.03.004--
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Rash23.03.13.001---
Rash erythematous23.03.13.029---
Rash maculo-papular23.03.13.004--
Renal tubular necrosis20.01.07.003---
Therapeutic response decreased08.06.01.016---
Urticaria10.01.06.001; 23.04.02.001--
Renal impairment20.01.03.010---
Acute kidney injury20.01.03.016--
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