Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Abrocitinib
Drug ID BADD_D02527
Description Abrocitinib is under investigation in clinical trial NCT03796676 (JAK1 Inhibitor With Medicated Topical Therapy in Adolescents With Atopic Dermatitis).
Indications and Usage Not Available
Marketing Status investigational
ATC Code D11AH08
DrugBank ID DB14973
KEGG ID D11400
MeSH ID C000634427
PubChem ID Not Available
TTD Drug ID Not Available
NDC Product Code 53869-1335; 0069-0235; 63539-236; 63539-336; 63539-436; 53869-1435; 0069-0335; 0069-0435; 53869-1235
UNII 73SM5SF3OR
Synonyms abrocitinib | N-(cis-3-(Methyl(7H-pyrrolo(2,3-d)pyrimidin-4-yl)amino)cyclobutyl)-1-propanesulfonamide | N-(cis-3-(Methyl(7H-pyrrolo(2,3-d)pyrimidin-4-yl)amino)cyclobutyl)-propane-1-sulfonamide | 1-Propanesulfonamide, N-(cis-3-(methyl-7H-pyrrolo(2,3-d)pyrimidin-4-ylamino)cyclobutyl)- | PF-04965842
Chemical Information
Molecular Formula Not Available
CAS Registry Number 1622902-68-4
SMILES Not Available
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pyrexia08.05.02.003--
Rash23.03.13.0010.001383%-
Rash erythematous23.03.13.0290.000603%-
Skin disorder23.03.03.007---
Skin lesion23.03.03.0100.000692%-
Sleep disorder19.02.04.0010.000603%-
Swelling08.01.03.0150.000390%-
Swelling face08.01.03.100; 10.01.05.018; 23.04.01.0180.000177%-
Therapeutic response unexpected08.06.01.0010.002199%-
Urticaria10.01.06.001; 23.04.02.0010.001206%
Vomiting07.01.07.003--
Peripheral swelling02.05.04.015; 08.01.03.0530.001082%-
Deep vein thrombosis24.01.02.0030.000177%-
Exfoliative rash23.03.07.0060.000603%-
Post inflammatory pigmentation change23.05.03.0020.000603%-
Drug effect less than expected08.06.01.036---
Drug effective for unapproved indication08.06.01.037; 12.09.02.0010.000390%-
Therapeutic product effect decreased08.06.01.050---
Therapeutic product effect incomplete08.06.01.0520.004699%-
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