Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Aclidinium
Drug ID BADD_D02465
Description Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD). It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.
Indications and Usage Aclidinium bromide inhalation powder is indicated for the long-term, maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
Marketing Status approved
ATC Code Not Available
DrugBank ID DB08897
KEGG ID Not Available
MeSH ID Not Available
PubChem ID 11434515
TTD Drug ID D0VP1V
NDC Product Code Not Available
UNII K17VY42F6C
Synonyms Not Available
Chemical Information
Molecular Formula C26H30NO4S2+
CAS Registry Number 727649-81-2
SMILES C1C[N+]2(CCC1C(C2)OC(=O)C(C3=CC=CS3)(C4=CC=CS4)O)CCCOC5=CC=CC=C5
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Lip swelling07.05.04.005; 10.01.05.005; 23.04.01.0070.000955%-
Loss of consciousness17.02.04.0040.001172%-
Lung disorder22.02.07.0010.001476%-
Malaise08.01.01.0030.003516%
Memory impairment17.03.02.003; 19.20.01.0030.001693%
Nasal congestion22.04.04.0010.001693%
Nasal dryness22.04.03.002---
Oedema mouth07.05.04.001; 10.01.05.006; 23.04.01.0080.000434%-
Oral pain07.05.05.0340.001476%
Pneumothorax22.05.02.0030.000434%
Productive cough22.02.03.0050.000434%
Pruritus23.03.12.0010.001389%
Rash23.03.13.0010.003733%-
Rash pruritic23.03.13.0300.002214%-
Respiration abnormal22.02.01.0410.001476%-
Respiratory disorder22.02.07.0020.001476%-
Stomatitis07.05.06.0050.000955%
Swelling08.01.03.0150.000955%-
Swollen tongue07.14.02.003; 10.01.05.015; 23.04.01.0140.000651%-
Syncope02.11.04.015; 17.02.04.008; 24.06.02.0120.000434%
Tachycardia02.03.02.0070.001172%-
Throat irritation07.05.05.037; 22.12.03.0290.001910%-
Throat tightness19.01.02.005; 22.12.03.0310.000434%-
Tremor17.01.06.0020.001476%
Urinary retention20.02.02.0110.001085%
Urticaria10.01.06.001; 23.04.02.0010.001693%
Vision blurred06.02.06.007; 17.17.01.0100.001085%
Wheezing22.03.01.0090.003906%
Hypoacusis04.02.01.0060.002951%
Peripheral swelling02.05.04.015; 08.01.03.053---
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