Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Vinblastine
Drug ID BADD_D02358
Description Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
Indications and Usage For treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
Marketing Status approved
ATC Code L01CA01
DrugBank ID DB00570
KEGG ID D08675
MeSH ID D014747
PubChem ID 13342
TTD Drug ID D0W9MM
NDC Product Code Not Available
UNII 5V9KLZ54CY
Synonyms Vinblastine | Vincaleukoblastine | Lemblastine | Velban | Vinblastina Lilly | Velbe | Vinblastine Sulfate | Sulfate, Vinblastine | Vinblastinsulfat-Gry | Cellblastin | Vinblastin Hexal
Chemical Information
Molecular Formula C46H58N4O9
CAS Registry Number 865-21-4
SMILES CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8 N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Neuropathy peripheral17.09.03.003---
Nystagmus06.05.02.006; 17.02.02.006--
Pain08.01.08.004--
Pain in jaw15.02.01.003---
Pancytopenia01.03.03.003---
Paraesthesia17.02.06.005; 23.03.03.094--
Peptic ulcer07.04.07.001---
Pharyngitis07.05.07.004; 11.01.13.003; 22.07.03.004--
Phlebitis12.02.01.002; 24.12.03.004--
Photophobia06.01.01.004; 17.17.02.006--
Rectal haemorrhage07.12.03.001; 24.07.02.018--
Seizure17.12.03.001--
Sensory loss17.02.07.007---
Thrombocytopenia01.08.01.002---
Vertigo04.04.01.003; 17.02.12.002--
Vomiting07.01.07.003--
Acute coronary syndrome02.02.02.015; 24.04.04.011---
Inappropriate antidiuretic hormone secretion05.03.03.001; 14.05.07.001---
Haemorrhage24.07.01.002---
Ischaemia24.04.02.004---
Decreased appetite08.01.09.028; 14.03.01.005--
Ill-defined disorder08.01.03.049---
Bone marrow failure01.03.03.005--
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ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene