Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Vinblastine
Drug ID BADD_D02358
Description Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
Indications and Usage For treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
Marketing Status Prescription; Discontinued
ATC Code L01CA01
DrugBank ID DB00570
KEGG ID D08675
MeSH ID D014747
PubChem ID 13342
TTD Drug ID D0W9MM
NDC Product Code Not Available
Synonyms Vinblastine | Vincaleukoblastine | Lemblastine | Velban | Vinblastina Lilly | Velbe | Vinblastine Sulfate | Sulfate, Vinblastine | Vinblastinsulfat-Gry | Cellblastin | Vinblastin Hexal
Chemical Information
Molecular Formula C46H58N4O9
CAS Registry Number 865-21-4
SMILES CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8 N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001--Not Available
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Angina pectoris02.02.02.002; 24.04.04.002--
Asthenia08.01.01.001--Not Available
Bone pain15.02.01.001--
Cellulitis11.02.01.001; 23.09.01.001--Not Available
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Constipation07.02.02.001--
Deafness04.02.01.001--Not Available
Depression19.15.01.001--
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness02.01.02.004; 17.02.05.003; 24.06.02.007--
Enterocolitis haemorrhagic07.08.01.007; 24.07.02.006--Not Available
Extravasation08.01.03.008--Not Available
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal pain07.01.05.005--
Haemoglobin13.01.05.018--Not Available
Headache17.14.01.001--
Hypertension24.08.02.001--
Hypoaesthesia17.02.06.023--Not Available
Ileus07.13.01.001--
Leukopenia01.02.02.001--Not Available
Malaise08.01.01.003--
Myocardial infarction02.02.02.007; 24.04.04.009--
Nausea07.01.07.001--
Neoplasm16.16.02.001--Not Available
Neuritis17.09.03.001--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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