| Drug Name |
Vasopressin |
| Drug ID |
BADD_D02339 |
| Description |
Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour.[A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids.[A228013] Despite a wide variety of functions, exogenous vasopressin is primarily used to control blood pressure during systemic shock by increasing vasoconstriction and renal fluid reuptake by acting through V1 and V2 cellular receptors.[A228008, A228013, A228018, L31413]
The vasopressive effect of posterior pituitary gland extracts was noted in 1895, while vasopressin itself was not purified until 1951. It has been used for more than five decades for varying conditions, including variceal bleeding, diabetes insipidus, and, more recently, vasodilatory shock.[A228013] It is currently marketed under the trademark VASOSTRICT® by PAR Pharmaceuticals.[L31413] |
| Indications and Usage |
Vasopressin is indicated to increase blood pressure in adults in vasodilatory shock refractory to the application of fluids and catecholamines.[L31413] |
| Marketing Status |
approved |
| ATC Code |
Not Available |
| DrugBank ID |
DB00067
|
| KEGG ID |
D00101
|
| MeSH ID |
D014667
|
| PubChem ID |
644077
|
| TTD Drug ID |
D0N4OW
|
| NDC Product Code |
35207-0005; 41701-008; 55150-371; 71872-7014; 52416-127; 51662-1607; 0548-9701; 42023-220; 0517-1030; 42023-164; 42023-190; 42023-237; 71872-7264; 14799-3001; 42367-570; 51662-1623; 0517-1020; 51662-1314; 65219-039; 63586-0004; 42023-219; 55150-370; 70121-1642; 63323-930; 43598-085; 59651-242 |
| UNII |
Y4907O6MFD
|
| Synonyms |
Vasopressins | Antidiuretic Hormones | Antidiuretic Hormone | Hormone, Antidiuretic | beta-Hypophamine | beta Hypophamine | Pitressin | Vasopressin (USP) | Vasopressin |
