Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Valganciclovir
Drug ID BADD_D02326
Description Valganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections. As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
Indications and Usage Valganciclovir is an antiviral medication used for the treatment of cytomegalovirus infections.
Marketing Status approved; investigational
ATC Code J05AB14
DrugBank ID DB01610
KEGG ID D02495
MeSH ID D000077562
PubChem ID 135413535
TTD Drug ID D06GWF
NDC Product Code 69097-277; 31722-832; 50268-787; 60429-846; 70069-810; 71921-210; 27241-158; 55111-762; 61269-480; 0004-0038; 70010-051; 0904-6796; 63739-076; 68084-965; 71151-003
UNII GCU97FKN3R
Synonyms Valganciclovir | Ganciclovir L-valyl Ester | Ganciclovir L valyl Ester | Valcyt | Valganciclovir Hydrochloride | Valcyte
Chemical Information
Molecular Formula C14H22N6O5
CAS Registry Number 175865-60-8
SMILES CC(C)C(C(=O)OCC(CO)OCN1C=NC2=C1N=C(NC2=O)N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Abnormal dreams17.15.02.001; 19.02.03.001---
Acne23.02.01.001---
Agitation17.02.05.012; 19.06.02.001--
Alopecia23.02.02.001--
Amblyopia06.02.01.001---
Amnesia17.03.02.001; 19.20.01.001--
Anaemia01.03.02.001--
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anaphylactic shock10.01.07.002; 24.06.02.004---
Anxiety19.06.02.002--
Aplastic anaemia01.03.03.002---
Arrhythmia02.03.02.001---
Arthralgia15.01.02.001--
Ascites02.05.04.002; 07.07.01.001; 09.01.05.003--
Asthenia08.01.01.001---
Ataxia08.01.02.004; 17.02.02.001--
Back pain15.03.04.005--
Blindness06.02.10.003; 17.17.01.003---
Blood creatine phosphokinase increased13.04.01.001--
Blood creatinine decreased13.13.01.003---
Blood creatinine increased13.13.01.004--
Blood glucose decreased13.02.02.001---
Blood lactate dehydrogenase increased13.04.02.002--
Blood urine13.13.02.011---
Body temperature increased13.15.01.001---
Bronchitis11.01.09.001; 22.07.01.001--
Cachexia08.01.01.009; 14.03.02.001; 16.32.03.011---
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