Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Valdecoxib
Drug ID BADD_D02325
Description Valdecoxib was removed from the Canadian, U.S., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke.
Indications and Usage For the treatment of osteoarthritis and dysmenorrhoea
Marketing Status approved; investigational; withdrawn
ATC Code M01AH03
DrugBank ID DB00580
KEGG ID D02709
MeSH ID C406224
PubChem ID 119607
TTD Drug ID D0L6DA
NDC Product Code Not Available
UNII 2919279Q3W
Synonyms valdecoxib | Bextra | SC 65872 | SC-65872
Chemical Information
Molecular Formula C16H14N2O3S
CAS Registry Number 181695-72-7
SMILES CC1=C(C(=NO1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood creatine phosphokinase increased13.04.01.001--
Blood creatinine increased13.13.01.004--
Blood lactate dehydrogenase increased13.04.02.002--
Blood urea increased13.13.01.006---
Blood uric acid increased13.02.04.001---
Body temperature increased13.15.01.001---
Bradycardia02.03.02.002---
Brain neoplasm benign16.09.01.001; 17.18.01.001---
Breast neoplasm16.10.02.001; 21.05.01.004---
Breath odour07.01.06.002---
Bronchitis11.01.09.001; 22.07.01.001--
Bronchospasm10.01.03.012; 22.03.01.004--
Cardiac failure congestive02.05.01.002---
Cardiac murmur13.14.01.001---
Cardiomyopathy02.04.01.001---
Carotid artery stenosis17.08.02.001; 24.04.06.001---
Cataract06.06.01.001--
Cellulitis11.02.01.001; 23.11.02.004---
Cerebrovascular disorder17.08.02.002; 24.03.05.002---
Cervical dysplasia21.06.01.002---
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Chills08.01.09.001; 15.05.03.016--
Cholelithiasis09.03.01.002---
Coagulopathy01.01.02.001---
Colitis07.08.01.001--
Confusional state17.02.03.005; 19.13.01.001--
Conjunctival haemorrhage06.07.01.001; 24.07.05.001---
Conjunctivitis06.04.01.002; 11.01.06.012--
Constipation07.02.02.001--
Coronary artery disease02.02.01.001; 24.04.04.006---
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