Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Trimetrexate glucuronate
Drug ID BADD_D02293
Description Not Available
Indications and Usage Not Available
Marketing Status Not Available
ATC Code Not Available
DrugBank ID Not Available
KEGG ID D06239
MeSH ID C056321
PubChem ID 54949
TTD Drug ID Not Available
NDC Product Code Not Available
UNII L137U4A79K
Synonyms trimetrexate glucuronate | trimetrexate glucuronic acid combination | NSC 352122 | NSC-352122 | NeuTrexin
Chemical Information
Molecular Formula C25H33N5O10
CAS Registry Number 82952-64-5
SMILES CC1=C(C=CC2=C1C(=NC(=N2)N)N)CNC3=CC(=C(C(=C3)OC)OC)OC.C(=O)C(C(C(C(C(=O)O)O)O)O) O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Alanine aminotransferase increased13.03.04.005--
Anaemia01.03.02.001--
Aspartate aminotransferase increased13.03.04.011--
Asthenia08.01.01.001---
Blood bilirubin increased13.03.04.018--
Blood creatinine increased13.13.01.004--
Body temperature increased13.15.01.001---
Confusional state17.02.03.005; 19.13.01.001--
Dermatitis23.03.04.002---
Electrolyte imbalance14.05.01.002---
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014---
Haemoglobin13.01.05.018---
Hepatotoxicity09.01.07.009; 12.03.01.008---
Hypocalcaemia14.04.01.004--
Hyponatraemia14.05.04.002--
Nausea07.01.07.001--
Neurotoxicity12.03.01.011; 17.02.10.002---
Neutropenia01.02.03.004---
Neutrophil count13.01.06.046---
Platelet count13.01.04.011---
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Rash23.03.13.001---
Seizure17.12.03.001--
Thrombocytopenia01.08.01.002---
Vomiting07.01.07.003--
Blood alkaline phosphatase increased13.04.02.004--
The 1th Page    1    Total 1 Pages