Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Tramazoline
Drug ID BADD_D02256
Description Tramazoline is under investigation in clinical trial NCT01601509 (Nasal Tramazoline and Dexamethazone in Obstructive Sleep Apnea (OSA) Patients Tramazoline and).
Indications and Usage Not Available
Marketing Status investigational
ATC Code R01AA09
DrugBank ID DB13064
KEGG ID D08624
MeSH ID C005370
PubChem ID 5524
TTD Drug ID D0ZT8D
NDC Product Code Not Available
UNII SLE31693IV
Synonyms tramazoline | 2-(5,6,7,8-tetrahydro-1-naphthylamino)-2-imidazoline | tramazoline hydrochloride | tramazoline monohydrochloride | Rhinospray | Spray-Tish | Bisolnasal | Biciron | Ellatun | KB 227
Chemical Information
Molecular Formula C13H17N3
CAS Registry Number 1082-57-1
SMILES C1CCC2=C(C1)C=CC=C2NC3=NCCN3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agitation17.02.05.012; 19.06.02.001--
Arrhythmia02.03.02.001---
Asthenia08.01.01.001---
Blood pressure increased13.14.03.005---
Dermatitis23.03.04.002---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dysgeusia07.14.03.001; 17.02.07.003--
Epistaxis22.04.03.001; 24.07.01.005--
Fatigue08.01.01.002--
Gastrointestinal disorder07.11.01.001---
Hallucination19.10.04.003--
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Immune system disorder10.02.01.001---
Insomnia17.15.03.002; 19.02.01.002--
Nasal congestion22.04.04.001--
Nasal dryness22.04.03.002---
Nasal oedema22.04.03.012---
Nasopharyngitis11.01.13.002; 22.07.03.002---
Nausea07.01.07.001--
Nervous system disorder17.02.10.001---
Oedema08.01.07.006; 14.05.06.010---
Oedema mucosal08.01.06.012---
Palpitations02.11.04.012--
Pruritus23.03.12.001--
Rash23.03.13.001---
Rhinorrhoea22.12.03.021--
Skin disorder23.03.03.007---
Sneezing22.12.03.024--
Somnolence17.02.04.006; 19.02.05.003--
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