Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Tolterodine tartrate
Drug ID BADD_D02245
Description Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Indications and Usage For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).
Marketing Status approved; investigational
ATC Code G04BD07
DrugBank ID DB01036
KEGG ID D01148
MeSH ID D000068737
PubChem ID 9847786
TTD Drug ID D0BZ7W
NDC Product Code 16571-127; 0093-0018; 33342-098; 50090-3475; 59762-0800; 70436-160; 53104-7572; 53747-035; 64552-4002; 31722-607; 43975-322; 0009-5191; 50090-5995; 70518-2794; 0009-0420; 11014-0122; 10135-706; 55111-855; 29300-239; 31722-608; 31722-806; 33342-097; 0093-7164; 14593-901; 65862-394; 65977-0029; 71666-009; 0093-0010; 29300-240; 43975-323; 73152-026; 52286-0018; 10135-707; 65427-020; 70436-161; 0093-7163; 59762-0047; 59762-0048; 50370-0023; 27241-191; 27241-192; 59762-0170; 71205-319; 49706-1835; 31722-805; 0009-4541; 0009-4544; 0009-5190; 11014-0123; 11014-0374; 16571-126
UNII 5T619TQR3R
Synonyms Tolterodine Tartrate | Tartrate, Tolterodine | Tolterodine | Detrol | Detrol LA | Urotrol | PHA-686464B | PHA 686464B | PHA686464B | Detrusitol | Unidet
Chemical Information
Molecular Formula C26H37NO7
CAS Registry Number 124937-52-6
SMILES CC1=CC(=C(C=C1)O)C(CCN(C(C)C)C(C)C)C2=CC=CC=C2.C(C(C(=O)O)O)(C(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Accommodation disorder06.02.04.001---
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anaphylactic shock10.01.07.002; 24.06.02.004---
Anaphylactoid reaction10.01.07.003; 24.06.03.007---
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Asthenia08.01.01.001---
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Delusion19.10.01.001--
Dementia17.03.01.001; 19.20.02.001---
Diarrhoea07.02.01.001--
Disorientation17.02.05.015; 19.13.01.002---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry eye06.08.02.001--
Dry mouth07.06.01.002--
Dry skin23.03.03.001--
Dyspepsia07.01.02.001--
Dysuria20.02.02.002--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014---
Gastrointestinal pain07.01.05.005--
Hallucination19.10.04.003--
Headache17.14.01.001--
Infection11.01.08.002---
Influenza like illness08.01.03.010--
Memory impairment17.03.02.003; 19.20.01.003--
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