| Drug Name |
Tiotropium bromide monohydrate |
| Drug ID |
BADD_D02225 |
| Description |
Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma.[A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.[A180163,L7084,L7087,L7090,L7093]
Tiotropium is more specific for the subset of muscarinic receptors commonly found in the lungs than [ipratropium].[A180163]
Tiotropium was granted FDA approval on 30 January 2004.[L7084] |
| Indications and Usage |
Tiotropium powder for inhalation is indicated for the maintenance of bronchospasm in COPD and to prevent exacerbations of COPD.[L7084] A combination tiotropium and [olodaterol] metered inhalation spray is indicated for maintenance of COPD.[L7087] A tiotropium inhalation spray is indicated for the maintenance of bronchospasm in COPD, to prevent exacerbations of COPD, and to treat asthma in patients 12 or more years old.[L7090] A tiotropium metered inhalation spray is indicated for the maintenance of bronchospasm in COPD, to prevent exacerbations of COPD, and to treat asthma in patients 6 or more years old.[L7093] |
| Marketing Status |
approved |
| ATC Code |
R03BB04 |
| DrugBank ID |
DB01409
|
| KEGG ID |
D01929
|
| MeSH ID |
D000069447
|
| PubChem ID |
11431811
|
| TTD Drug ID |
D0P1WA
|
| NDC Product Code |
64567-0026; 66412-0761; 61662-0021; 63190-0380; 63190-0560 |
| UNII |
L64SXO195N
|
| Synonyms |
Tiotropium Bromide | Bromide, Tiotropium | 7-((hydroxybis(2-thienyl)acetyl)oxy)-9,9-dimethyl-3-oxa-9-azoniatricyclo(3.3.1.0(2,4))nonane bromide | Tiotropium | Spiriva | BA 679 BR | 679 BR, BA | BR, BA 679 | BA-679 BR | BA679 BR |
