| Pharmaceutical Information |
| Drug Name |
Sulconazole nitrate |
| Drug ID |
BADD_D02087 |
| Description |
Sulconazole, brand name Exelderm, is a broad-spectrum anti-fungal agent available as a topical cream and solution. Sulconazole nitrate, the active ingredient, is an imidazole derivative that inhibits the growth of common pathogenic dermatophytes making it an effective treatment for tinea cruris and tinea corporis infections. |
| Indications and Usage |
Sulconazole solution 1.0% is indicated for the treatment of tinea cruris and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis; and for the treatment of tinea versicolor. Effectiveness has not been proven in tinea pedis (athlete’s foot). |
| Marketing Status |
approved |
| ATC Code |
D01AC09 |
| DrugBank ID |
DB06820
|
| KEGG ID |
D00886
|
| MeSH ID |
C033308
|
| PubChem ID |
65495
|
| TTD Drug ID |
D0X8XA
|
| NDC Product Code |
49706-0845; 69489-721; 69489-711; 72143-321; 72143-311 |
| UNII |
1T89100D5U
|
| Synonyms |
sulconazole | 1-(beta-(4''-chlorobenzylthio)-2'4'-dichlorophenethyl)imidazole | sulconazole nitrate | Exelderm | Myk | sulconazole mononitrate | sulconazole, mononitrate, (+-)-isomer |
|
| Chemical Information |
| Molecular Formula |
C18H16Cl3N3O3S |
| CAS Registry Number |
61318-91-0 |
| SMILES |
C1=CC(=CC=C1CSC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-] |
| Chemical Structure |
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| ADRs Induced by Drug |
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*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
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| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
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ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
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| Erythema | 23.03.06.001 | - | - | - | | Pain | 08.01.08.004 | - | - | | | Pruritus | 23.03.12.001 | - | - | |
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