Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Succimer
Drug ID BADD_D02078
Description A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.
Indications and Usage For the treatment of lead poisoning in pediatric patients with blood lead levels above 45 µg/dL. May also be used to treat mercury or arsenic poisoning.
Marketing Status approved
ATC Code Not Available
DrugBank ID DB00566
KEGG ID D00572
MeSH ID D004113
PubChem ID 2724354
TTD Drug ID D01GYK
NDC Product Code 65085-0072; 71083-0020; 55679-117; 55292-201; 38779-0780; 70086-124
UNII DX1U2629QE
Synonyms Succimer | DMSA | meso-Dimercaptosuccinic Acid | Acid, meso-Dimercaptosuccinic | meso Dimercaptosuccinic Acid | Butanedioic Acid, 2,3-Dimercapto-, (R*,S*)-Isomer | Succicaptal | Succimer Antimony Sodium Salt, (R*,S*)-Isomer | Succimer, (R*,R*)-(+,-)-Isomer | Succimer, Dipotassium Salt | Dipotassium Salt Succimer | 2,3-Dimercaptosuccinic Acid | 2,3 Dimercaptosuccinic Acid | Acid, 2,3-Dimercaptosuccinic | Dimercaptosuccinic Acid | Acid, Dimercaptosuccinic | Succimer, Monosodium Salt | Monosodium Salt Succimer | Succimer, Rhenium Salt | Rhenium Salt Succimer | Chemet | Succimer, Tin Salt | Tin Salt Succimer | Tin Dimercaptosuccinate | Dimercaptosuccinate, Tin | Ro-1-7977 | Ro 1 7977 | Ro17977 | Succimer, Disodium Salt | Disodium Salt Succimer
Chemical Information
Molecular Formula C4H6O4S2
CAS Registry Number 304-55-2
SMILES C(C(C(=O)O)S)(C(=O)O)S
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Neuropathy peripheral17.09.03.003---
Neutropenia01.02.03.004---
Otitis media04.05.01.001; 11.01.05.004--
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Paraesthesia17.02.06.005; 23.03.03.094--
Proteinuria20.02.01.011--
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Rash23.03.13.001---
Rash papular23.03.13.017---
Rash vesicular23.03.13.009---
Rhinitis11.01.13.004; 22.07.03.006--
Rhinorrhoea22.12.03.021--
Somnolence17.02.04.006; 19.02.05.003--
Strangury20.02.02.017---
Thrombocytosis01.08.02.001---
Vision blurred06.02.06.007; 17.17.01.010--
Vomiting07.01.07.003--
Musculoskeletal chest pain15.03.04.012; 22.09.01.001--
Platelet count increased13.01.04.002---
Ear discomfort04.03.01.005---
Protein urine present13.13.02.006---
Mucocutaneous rash23.03.13.011---
Peripheral sensorimotor neuropathy17.09.03.009---
Decreased appetite08.01.09.028; 14.03.01.005--
Oropharyngeal discomfort07.05.05.008; 22.12.03.015---
Oropharyngeal pain07.05.05.004; 22.12.03.016--
Candida infection11.03.03.021--
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