Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Streptokinase
Drug ID BADD_D02070
Description Streptokinase, is a sterile, purified preparation of a bacterial protein elaborated by group C (beta) -hemolytic streptococci.
Indications and Usage For the treatment of acute evolving transmural myocardial infarction, pulmonary embolism, deep vein thrombosis, arterial thrombosis or emolism and occlusion of arteriovenous cannulae
Marketing Status approved; investigational
ATC Code B01AD01
DrugBank ID DB00086
KEGG ID D06879
MeSH ID D013300
PubChem ID 9815560
TTD Drug ID D04URO
NDC Product Code Not Available
UNII 8X1OXL3SNU
Synonyms Streptokinase | Streptase | Streptodecase | Kabikinase | Awelysin | Celiase | Distreptase | Kabivitrum | Avelizin
Chemical Information
Molecular Formula C11H19NO2
CAS Registry Number 9002-01-1
SMILES C1CCC(CC1)C2CC(NC2)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic shock10.01.07.002; 24.06.02.004---
Anaphylactoid reaction10.01.07.003; 24.06.03.007---
Angina pectoris02.02.02.002; 24.04.04.002--
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Arthritis15.01.01.001--
Asthenia08.01.01.001---
Back pain15.03.04.005--
Body temperature increased13.15.01.001---
Bradycardia02.03.02.002---
Bronchospasm10.01.03.012; 22.03.01.004--
Cardiac arrest02.03.04.001--
Cardiac failure02.05.01.001--
Cerebral haemorrhage17.08.01.003; 24.07.04.001---
Chills08.01.09.001; 15.05.03.016--
Death08.04.01.001--
Dermatitis23.03.04.002---
Discomfort08.01.08.003---
Dyspnoea02.11.05.003; 22.02.01.004--
Eye swelling06.08.03.003---
Feeling abnormal08.01.09.014---
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Guillain-Barre syndrome10.04.10.005; 11.07.01.001; 17.09.01.001--
Haematocrit decreased13.01.05.001---
Haemoglobin13.01.05.018---
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Hypotension24.06.03.002--
Malaise08.01.01.003--
Musculoskeletal pain15.03.04.007--
Myalgia15.05.02.001--
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