Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Spinosad
Drug ID BADD_D02065
Description Spinosad is a pediculicide mixture of spinosyn A and spinosyn D (in an approximately 5:1 ratio, respectively) used in the topical treatment of head lice in children (four years old and older) and in adults. Spinosad is an insecticide based on a compound found in S. spinosa, a bacterial species. Spinosad has also been experimented for use in cats for treatment of flea infestations, and has also been experimented for use against the KS1 Ctenocephalides felis flea strain infesting dogs, in addition to many investigations for use in other animals and agricultural plants.
Indications and Usage Spinosad is indicated for the topical treatment of head lice in children four years old and over and in adults.
Marketing Status approved; investigational; vet_approved
ATC Code Not Available
DrugBank ID DB08823
KEGG ID D09384
MeSH ID C415329
PubChem ID 56841558
TTD Drug ID D09WCM
NDC Product Code 52246-929; 28595-570; 62227-020; 62158-0009
UNII XPA88EAP6V
Synonyms spinosad
Chemical Information
Molecular Formula C83H132N2O20
CAS Registry Number 168316-95-8
SMILES CCC1CCCC(C(C(=O)C2=CC3C4CC(CC4C=CC3C2CC(=O)O1)OC5C(C(C(C(O5)C)OC)OC)OC)C)OC6CCC( C(O6)C)N(C)C.CCC1CCCC(C(C(=O)C2=CC3C4CC(CC4C(=CC3C2CC(=O)O1)C)OC5C(C(C(C(O5)C)OC )OC)OC)C)OC6CCC(C(O6)C)N(C)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Alopecia23.02.02.001--
Application site erythema08.02.01.001; 12.07.01.001; 23.03.06.005---
Application site irritation08.02.01.003; 12.07.01.003---
Dry skin23.03.03.001--
Erythema23.03.06.001---
Erythema of eyelid06.04.04.003; 23.03.06.006---
Application site dryness08.02.01.011; 12.07.01.011; 23.03.03.024---
Application site exfoliation08.02.01.022; 12.07.01.022; 23.03.07.007---
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