Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Rizatriptan benzoate
Drug ID BADD_D01958
Description Rizatriptan is a triptan drug used for the treatment of migraine headaches. It is a selective 5-hydroxytryptamine1 receptor subtype agonist.
Indications and Usage For treatment of acute migraine attacks with or without aura.
Marketing Status approved
ATC Code N02CC04
DrugBank ID DB00953
KEGG ID D00675
MeSH ID C093622
PubChem ID 77997
TTD Drug ID D0S9MU
NDC Product Code 78206-143; 64220-996; 65862-578; 0093-7471; 57237-088; 72189-258; 72189-316; 78206-142; 65372-1147; 43817-133; 65862-625; 71205-644; 53104-7580; 64567-0013; 65862-626; 33342-093; 51991-354; 51991-355; 57237-086; 59746-415; 63187-563; 63629-7433; 68462-465; 71335-1346; 72189-447; 61919-394; 68462-468; 71335-1149; 65862-599; 67877-262; 69452-157; 71205-398; 71335-1577; 66039-835; 29300-317; 50090-3367; 53002-1713; 61919-656; 69097-865; 72189-126; 29300-268; 33342-094; 43817-135; 57237-085; 59746-414; 63629-8256; 65862-600; 68462-467; 71335-2031; 51991-363; 0378-1403; 67877-261; 68462-466; 70518-2957; 71205-557; 71335-0810; 71335-1912; 14593-872; 67835-5016; 53002-3713; 55700-942; 69097-866; 70518-0509; 55111-092; 29300-316; 55700-958; 57237-087; 0378-1404; 69452-156; 53747-043; 64220-995; 65015-653; 0093-7472; 29300-269; 50090-3343; 51991-362
UNII WR978S7QHH
Synonyms rizatriptan | N,N-dimethyl-2-(5-(1,2,4-triazol-1-ylmethyl)-1H-indole-3-yl)ethylamine | rizatriptan benzoate | MK 0462 | MK-0462 | MK-462 | MK 462 | L 705,126 | L-705,126 | L-705126 | L 705126 | Maxalt
Chemical Information
Molecular Formula C22H25N5O2
CAS Registry Number 145202-66-0
SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3.C1=CC=C(C=C1)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Peripheral coldness08.01.09.010; 23.06.04.008; 24.04.03.006---
Pharyngeal oedema10.01.05.016; 22.04.05.003; 23.04.01.016---
Presyncope02.11.04.013; 17.02.05.009; 24.06.02.010--
Pruritus23.03.12.001--
Rash23.03.13.001---
Seizure17.12.03.001--
Serotonin syndrome12.03.01.041; 15.05.04.016; 17.05.02.004---
Shock24.06.02.002---
Somnolence17.02.04.006; 19.02.05.003--
Swelling08.01.03.015---
Swollen tongue07.14.02.003; 10.01.05.015; 23.04.01.014---
Syncope02.11.04.015; 17.02.04.008; 24.06.02.012--
Tachycardia02.03.02.007---
Tension19.06.02.005---
Thirst08.01.09.021; 14.03.02.007---
Throat tightness19.01.02.005; 22.12.03.031---
Tinnitus04.04.01.002; 17.04.07.004--
Tongue oedema07.14.02.007; 10.01.05.008; 23.04.01.009---
Toxic epidermal necrolysis10.01.01.006; 11.07.01.006; 12.03.01.015; 23.03.01.008--
Tremor17.01.06.002--
Urticaria10.01.06.001; 23.04.02.001--
Vertigo04.04.01.003; 17.02.12.002--
Vision blurred06.02.06.007; 17.17.01.010--
Vomiting07.01.07.003--
Wheezing22.03.01.009--
Hypoacusis04.02.01.006--
Muscle tightness15.05.03.007---
Musculoskeletal stiffness15.03.05.027---
Musculoskeletal discomfort15.03.04.001---
Angiopathy24.03.02.007---
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